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NCT07124533 · ClinicalTrials.gov registry record · Phase 3

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

A Phase 3 study, sponsored by Loma Linda University.

Not yet
Registry status
Phase 3
Development phase
50
Enrollment target

NCT07124533: Clinical Trial Phase 3 study, sponsored by Loma Linda University.

NCT07124533 is a Phase 3 study that has not yet begun recruiting, run by Loma Linda University. The registered enrollment target is 50 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07124533, a Phase 3 study, has not yet begun recruiting, sponsored by Loma Linda University.

NOT YET RECRUITING
Registry status
Phase 3
Development phase
50 participants
Enrollment target

Study Summary

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Primary Outcome

The quantity of plaque build-up is measured visually using the Quigley-Hein Plaque Index. The Plaque index can range from 0 to 5, with higher numbers indicating more plaque build-up.

Interventions

  • DRUG Toothpaste Tablet
  • DRUG Conventional Toothpaste

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-12
Est. Completion 2026-12
Phase Phase 3
Loma Linda University

237 total trials

What is known before NCT07124533 opens enrollment

NCT07124533 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which Toothpaste Tablet is the first listed.

NCT07124533 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07124533 about?

NCT07124533 is a clinical study titled "Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences". Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned d...

What is the current status of trial NCT07124533?

This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 50 participants. The study started on 2026-12. Estimated completion is 2026-12.

What interventions are being tested in trial NCT07124533?

The interventions under investigation include: Toothpaste Tablet (DRUG), Conventional Toothpaste (DRUG).

Who is sponsoring clinical trial NCT07124533?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07124533's enrollment target sits among peer trials

50 1844th of 2000 higher than 141 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07124533, the US trial registry maintained by the National Library of Medicine. NCT07124533 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.