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NCT07120997 · ClinicalTrials.gov registry record · NA
Prunes Preventing Bone Loss in Perimenopause
A NA study of Perimenopausal Bone Loss, sponsored by Penn State University.
- Recruiting
- Registry status
- NA
- Development phase
- 124
- Enrollment target
- 1
- Study location
NCT07120997 is a NA study of Perimenopausal Bone Loss that is actively recruiting participants, run by Penn State University. The registered enrollment target is 124 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07120997, a NA study of Perimenopausal Bone Loss, is actively recruiting participants, sponsored by Penn State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 124 participants
- Enrollment target
- 1
- Study location
Study Summary
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss which, if successfully attenuated, can potentially prevent/delay osteoporosis in women. The transmenopausal period represents an opportunistic window for the study because bone loss is at its greatest at this time, with females losing as much as 6-7% of bone. If this project is successful at attenuating bone loss, it can immediately be disseminated to the public to promote prune consumption to slow down and attenuate perimenopausal bone loss. As such, this project could improve the long-term bone health of females and avoid or delay osteoporosis and improve quality of life. The long-term goal of this study is to test the novel hypothesis that prune consumption for 18 months during the 3-year transmenopausal period prevents the dramatic rate of bone loss in perimenopausal females during a window of heightened physiological vulnerability. At Penn State University, the study will compare the effects of 18 months of daily dietary consumption of 50 g of prunes (5-6) versus a no-prune control group on bone outcomes (bone mineral density, bone geometry), mechanistic factors (bone and inflammatory markers, inflammatory response of ex vivo cultured peripheral blood mononuclear cells, monocytes), and gut microbiome.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Prunes
- DIETARY_SUPPLEMENT Calcium supplement
- DIETARY_SUPPLEMENT Vitamin D Supplement
Study Locations (1)
Pennsylvania
- Women's Health and Exercise Laboratory, The Pennsylvania State University - University Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2025-12-11 |
| Est. Completion | 2029-12 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07120997
The ClinicalTrials.gov registry entry for NCT07120997 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 124 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Penn State University, which has 219 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Perimenopausal Bone Loss appearing as the primary indexed condition, and to 3 interventions - of which Prunes is the first listed.
NCT07120997 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07120997 about?
NCT07120997 is a clinical study titled "Prunes Preventing Bone Loss in Perimenopause". Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss which, if successfully attenuated, can potentially prevent/delay osteoporosi...
What is the current status of trial NCT07120997?
This trial is currently recruiting. It is a NA study. The enrollment target is 124 participants. The study started on 2025-12-11. Estimated completion is 2029-12.
What conditions does trial NCT07120997 study?
This clinical trial studies the following conditions: Perimenopausal Bone Loss.
What interventions are being tested in trial NCT07120997?
The interventions under investigation include: Prunes (DIETARY_SUPPLEMENT), Calcium supplement (DIETARY_SUPPLEMENT), Vitamin D Supplement (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07120997?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07120997 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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