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NCT07104084 · ClinicalTrials.gov registry record · NA
Influence of Antiseptic Washes on Wound Healing Complications After THA
A NA study of Hip Osteoarthritis and Avascular Necrosis of Femur Head, sponsored by F. Johannes Plate.
- Recruiting
- Registry status
- NA
- Development phase
- 420
- Enrollment target
- 2
- Study locations
NCT07104084: Recruiting NA study of Hip Osteoarthritis and Avascular Necrosis of Femur Head, sponsored by F. Johannes Plate.
NCT07104084 is a NA study of Hip Osteoarthritis and Avascular Necrosis of Femur Head that is actively recruiting participants, run by F. Johannes Plate. The registered enrollment target is 420 participants, above the 367-participant average among 11 other Hip Osteoarthritis trials with a reported enrollment target (14% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07104084, a NA study of Hip Osteoarthritis and Avascular Necrosis of Femur Head, is actively recruiting participants, sponsored by F. Johannes Plate.
- RECRUITING
- Registry status
- NA
- Development phase
- 420 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery. Washing solutions are used routinely during total hip replacements to clean the wound after the components have been placed and the wound is about to be closed with sutures. It is currently not known which washing solution may be better for wound healing and whether a certain solution decreases the risk of wound healing complications after total hip replacement. Therefore, this research trial is being conducted. Study participants will be randomized into one of two groups: washing the surgical wound with povidone-iodine solution (Surgiphor, Becton Dickinson, Franklin Lakes, NJ) or chlorhexidine solution (Irrisept, Irrimax Corporation, Lawrenceville, GA). All patients will undergo standard of care total hip replacements without any other change in surgery. The best type of solution that cleans the wound and potentially leads to better wound healing is unknown. This study will evaluate whether there is difference in surgical wound healing between the two washing solutions. The study will pay for the washing solutions. Patients will follow up for standard postoperative visits. At the 2-week and 6-week visits, pictures of the surgical incision will be taken and saved in the electronic medical record and evaluated in a standardized way for healing of the incision and the appearance of the scar. Postoperative complications and returns to the hospital or additional surgeries will be collected from the electronic medical record.
Primary Outcome
The observer scale of the POSAS consists of six items (vascularity, pigmentation, thickness, relief, pliability and surface area). All items are scored on a scale ranging from 1 ('like normal skin') to 10 ('worst scar imaginable'). The sum of the six items results in a total score of the POSAS observer scale. Categories boxes are added for each item. Furthermore, an overall opinion is scored on a scale ranging from 1 to 10. All parameters should preferably be compared to normal skin on a compara
Conditions Studied
Interventions
- DEVICE lavage chlorhexidine
- DEVICE lavage povidone-iodine
Study Locations (2)
Pennsylvania
- UPMC East - Monroeville
- UPMC Shadyside - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 420 participants |
| Start Date | 2025-10-09 |
| Est. Completion | 2028-01-01 |
| Phase | NA |
What NCT07104084 shows while recruiting
NCT07104084 is an interventional study that assigns participants to a tested intervention. The registered 420 participants enrollment target is mid-sized for trials with a published cap, above the 367-participant average among 11 other Hip Osteoarthritis trials with a reported enrollment target (14% higher).
The record links to 2 conditions, with Hip Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which lavage chlorhexidine is the first listed.
NCT07104084 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07104084 about?
NCT07104084 is a clinical study titled "Influence of Antiseptic Washes on Wound Healing Complications After THA". The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery. Washing solutions are used routinely during total hip replacements to clean the wound after the components have been placed and the wound is about to b...
What is the current status of trial NCT07104084?
This trial is currently recruiting. It is a NA study. The enrollment target is 420 participants. The study started on 2025-10-09. Estimated completion is 2028-01-01.
What conditions does trial NCT07104084 study?
This clinical trial studies the following conditions: Hip Osteoarthritis, Avascular Necrosis of Femur Head.
What interventions are being tested in trial NCT07104084?
The interventions under investigation include: lavage chlorhexidine (DEVICE), lavage povidone-iodine (DEVICE).
Who is sponsoring clinical trial NCT07104084?
This trial is sponsored by F. Johannes Plate, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07104084 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hip Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07104084's enrollment target sits among peer trials
420 3rd of 11 higher than 9 of 11 other Hip Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hip Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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