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NCT07083531 · ClinicalTrials.gov registry record

Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait

A clinical trial of Sickle Cell Disease and Sickle Cell Trait, sponsored by UConn Health.

Recruiting
Registry status
50
Enrollment target
1
Study location

NCT07083531: Recruiting study of Sickle Cell Disease and Sickle Cell Trait, sponsored by UConn Health.

NCT07083531 is a study of Sickle Cell Disease and Sickle Cell Trait that is actively recruiting participants, run by UConn Health. The registered enrollment target is 50 participants, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07083531, a study of Sickle Cell Disease and Sickle Cell Trait, is actively recruiting participants, sponsored by UConn Health.

RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes. The first purpose is to determine whether having SCT is a risk factor for the development of bone thinning in older women. The second purpose is to investigate whether women with SCT have reduced muscle function and increased frailty compared to women without SCT. The investigators estimate enrolling 50 female volunteers who are at least 50 years old and have not had a menstrual period for at least 12 consecutive months. Volunteers need not know whether they have SCT as this will be evaluated as part of the study.

Primary Outcome

Particpants will undergo dual energy xray absorptiometry.

Interventions

  • OTHER Healthy volunteers without SCT
  • OTHER Healthy volunteers with SCT

Study Locations (1)

Connecticut

  • UConn Health - Farmington

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2022-08-23
Est. Completion 2025-08-23
UConn Health

178 total trials

What NCT07083531 shows while recruiting

NCT07083531 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (83% lower).

The record links to 2 conditions, with Sickle Cell Disease appearing as the primary indexed condition, and to 2 interventions - of which Healthy volunteers without SCT is the first listed.

NCT07083531 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT07083531 about?

NCT07083531 is a clinical study titled "Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait". This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes. The first purpose is to determine whether having SCT is a risk factor for the devel...

What is the current status of trial NCT07083531?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2022-08-23. Estimated completion is 2025-08-23.

What conditions does trial NCT07083531 study?

This clinical trial studies the following conditions: Sickle Cell Disease, Sickle Cell Trait.

What interventions are being tested in trial NCT07083531?

The interventions under investigation include: Healthy volunteers without SCT (OTHER), Healthy volunteers with SCT (OTHER).

Who is sponsoring clinical trial NCT07083531?

This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07083531 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Sickle Cell Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07083531's enrollment target sits among peer trials

50 106th of 213 higher than 100 of 213 other Sickle Cell Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Sickle Cell Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07083531, the US trial registry maintained by the National Library of Medicine. NCT07083531 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.