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NMBA Reversal and Postoperative Urinary Retention
NCT06948409 · View on ClinicalTrials.gov ↗
Study Summary
In this single-center retrospective cohort study of adult patients who underwent surgery under general anesthesia at Beth Israel Deaconess Medical Center between September 2016 and January 2024, the association between the choice of neuromuscular blocking agent (NMBA) reversal strategy, comparing sugammadex with neostigmine (combined with a muscarinic antagonist), and postoperative urinary retention (POUR) will be evaluated. In secondary analyses, the effects of NMBA reversal strategy and POUR on costs of care and unplanned hospital visits will be analyzed.
Conditions Studied
Interventions
- DRUG Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist])
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center — Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70,000 participants |
| Start Date | 2025-06-08 |
| Est. Completion | 2026-06-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06948409
The ClinicalTrials.gov registry entry for NCT06948409 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 70,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 434 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Neuromuscular Blockade appearing as the primary indexed condition, and to 1 intervention — of which Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist]) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06948409 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06948409 about?
NCT06948409 is a clinical study titled "NMBA Reversal and Postoperative Urinary Retention". In this single-center retrospective cohort study of adult patients who underwent surgery under general anesthesia at Beth Israel Deaconess Medical Center between September 2016 and January 2024, the association between the choice of neuromuscular blocking agent (NMBA) reversal strategy, comparing su...
What is the current status of trial NCT06948409?
This trial is currently active not recruiting. The enrollment target is 70,000 participants. The study started on 2025-06-08. Estimated completion is 2026-06-01.
What conditions does trial NCT06948409 study?
This clinical trial studies the following conditions: Neuromuscular Blockade, Urinary Retention Postoperative, Sugammadex, Neuromuscular Blocking Agents, Urinary Retention After Procedure. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06948409?
The interventions under investigation include: Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist]) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06948409?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 434 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06948409 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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