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NCT06948201 · ClinicalTrials.gov registry record · NA
Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA
A NA study, sponsored by University of Virginia.
- Not yet
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT06948201: Clinical Trial NA study, sponsored by University of Virginia.
NCT06948201 is a NA study that has not yet begun recruiting, run by University of Virginia. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06948201, a NA study, has not yet begun recruiting, sponsored by University of Virginia.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to see if inorganic nitrate in the form of beetroot juice helps blood flow and physical fitness in women with ANOCA and CMD. The main questions it aims to answer are: AIM 1: Test the hypothesis that fourteen days of nitrate rich beetroot juice will increase cardiac perfusion and improve quality of life compared to placebo. AIM 2: Test the hypothesis that fourteen days of nitrate rich beetroot juice will increase physical fitness and reduce angina and dyspnea symptoms compared to placebo. Exploratory AIM 3: Test the hypothesis that fourteen days of nitrate rich beetroot juice will improve vascular health and function. Participants will: * Take study beverage for 4 weeks total. * Stress Cardiac magnetic resonance imaging and 12 lead electrocardiograms * Complete questionnaires * Cycling exercise test * Non invasive vascular testing * Blood draws
Primary Outcome
Coronary flow reserve is calculated as the ratio of hyperemic myocardial blood flow to the resting myocardial blood flow using cardiovascular magnetic resonance myocardial perfusion imaging
Interventions
- DIETARY_SUPPLEMENT 70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice)
- DIETARY_SUPPLEMENT Placebo (70 mL Nitrate depleted beetroot juice) followed by 70mL Nitrate Rich Beetroot Juice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2025-05 |
| Est. Completion | 2026-06 |
| Phase | NA |
What is known before NCT06948201 opens enrollment
NCT06948201 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which 70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice) is the first listed.
NCT06948201 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06948201 about?
NCT06948201 is a clinical study titled "Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA". The purpose of this study is to see if inorganic nitrate in the form of beetroot juice helps blood flow and physical fitness in women with ANOCA and CMD. The main questions it aims to answer are: AIM 1: Test the hypothesis that fourteen days of nitrate rich beetroot juice will increase cardiac perf...
What is the current status of trial NCT06948201?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 8 participants. The study started on 2025-05. Estimated completion is 2026-06.
What interventions are being tested in trial NCT06948201?
The interventions under investigation include: 70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice) (DIETARY_SUPPLEMENT), Placebo (70 mL Nitrate depleted beetroot juice) followed by 70mL Nitrate Rich Beetroot Juice (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06948201?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06948201's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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