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NCT06925152 · ClinicalTrials.gov registry record · Phase 4
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
A Phase 4 study of Cesarean Delivery and Postoperative Pain Control, sponsored by University of Tennessee.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06925152: Recruiting Phase 4 study of Cesarean Delivery and Postoperative Pain Control, sponsored by University of Tennessee.
NCT06925152 is a Phase 4 study of Cesarean Delivery and Postoperative Pain Control that is actively recruiting participants, run by University of Tennessee. The registered enrollment target is 120 participants, below the 3,471-participant average among 10 other Cesarean Delivery trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06925152, a Phase 4 study of Cesarean Delivery and Postoperative Pain Control, is actively recruiting participants, sponsored by University of Tennessee.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).
Primary Outcome
Total pain medication requested expressed in morphine milligram equivalents.
Conditions Studied
Interventions
- DRUG Bupivicaine intervention arm
- DRUG Placebo arm
Study Locations (1)
Tennessee
- Regional One Health - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-07-15 |
| Est. Completion | 2028-05 |
| Phase | Phase 4 |
What NCT06925152 shows while recruiting
NCT06925152 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 3,471-participant average among 10 other Cesarean Delivery trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Cesarean Delivery appearing as the primary indexed condition, and to 2 interventions - of which Bupivicaine intervention arm is the first listed.
NCT06925152 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT06925152 about?
NCT06925152 is a clinical study titled "COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block". To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).
What is the current status of trial NCT06925152?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2025-07-15. Estimated completion is 2028-05.
What conditions does trial NCT06925152 study?
This clinical trial studies the following conditions: Cesarean Delivery, Postoperative Pain Control, Complex Obstetric Surgery, Perioperative Pain Management.
What interventions are being tested in trial NCT06925152?
The interventions under investigation include: Bupivicaine intervention arm (DRUG), Placebo arm (DRUG).
Who is sponsoring clinical trial NCT06925152?
This trial is sponsored by University of Tennessee, which has 96 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06925152 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cesarean Delivery
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06925152's enrollment target sits among peer trials
120 6th of 10 higher than 5 of 10 other Cesarean Delivery trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cesarean Delivery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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