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NCT06861244 · ClinicalTrials.gov registry record · Phase 2
Embryonal Tumor With Multilayered Rosettes
A Phase 2 study of Embryonal Tumor With Multilayered Rosettes and Embryonal Tumor With Multilayered Rosettes, Nos, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 70
- Enrollment target
- 4
- Study locations
NCT06861244: Recruiting Phase 2 study of Embryonal Tumor With Multilayered Rosettes and Embryonal Tumor With Multilayered Rosettes, Nos, sponsored by University of California, San Francisco.
NCT06861244 is a Phase 2 study of Embryonal Tumor With Multilayered Rosettes and Embryonal Tumor With Multilayered Rosettes, Nos that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 70 participants, below the 134-participant average among 3 other Embryonal Tumor With Multilayered Rosettes trials with a reported enrollment target (48% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06861244, a Phase 2 study of Embryonal Tumor With Multilayered Rosettes and Embryonal Tumor With Multilayered Rosettes, Nos, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 70 participants
- Enrollment target
- 4
- Study locations
Study Summary
This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).
Primary Outcome
The median PFS6 is defined as the median number of months for participants in Cohort 1 who have remained progression-free from the date of initial surgical resection until 6 months.
Conditions Studied
Interventions
- DRUG Temozolomide
- RADIATION Radiotherapy (RT)
- DRUG Chemotherapy Drug, Cancer - Physician's Choice
- PROCEDURE Non-Investigational Surgical Resection
- PROCEDURE Tumor Tissue Sample
Study Locations (4)
Alabama
- University of Alabama at Birmingham - Birmingham
California
- University of California, San Francisco - San Francisco
Maryland
- Johns Hopkins University - Baltimore
Missouri
- Washington University in St. Louis - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-03-06 |
| Est. Completion | 2032-03-31 |
| Phase | Phase 2 |
What NCT06861244 shows while recruiting
NCT06861244 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 134-participant average among 3 other Embryonal Tumor With Multilayered Rosettes trials with a reported enrollment target (48% lower).
The record links to 2 conditions, with Embryonal Tumor With Multilayered Rosettes appearing as the primary indexed condition, and to 5 interventions - of which Temozolomide is the first listed.
NCT06861244 reports a single indexed study location in Alabama, California, Maryland.
Frequently Asked Questions
What is clinical trial NCT06861244 about?
NCT06861244 is a clinical study titled "Embryonal Tumor With Multilayered Rosettes". This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).
What is the current status of trial NCT06861244?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2025-03-06. Estimated completion is 2032-03-31.
What conditions does trial NCT06861244 study?
This clinical trial studies the following conditions: Embryonal Tumor With Multilayered Rosettes, Embryonal Tumor With Multilayered Rosettes, Nos.
What interventions are being tested in trial NCT06861244?
The interventions under investigation include: Temozolomide (DRUG), Radiotherapy (RT) (RADIATION), Chemotherapy Drug, Cancer - Physician's Choice (DRUG), Non-Investigational Surgical Resection (PROCEDURE), Tumor Tissue Sample (PROCEDURE).
Who is sponsoring clinical trial NCT06861244?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06861244 being conducted?
This trial has 4 study locations across Alabama, California, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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