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Embryonal Tumor With Multilayered Rosettes
NCT06861244 · View on ClinicalTrials.gov ↗
Study Summary
This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).
Conditions Studied
Interventions
- DRUG Temozolomide
- RADIATION Radiotherapy (RT)
- DRUG Chemotherapy Drug, Cancer - Physician's Choice
- PROCEDURE Non-Investigational Surgical Resection
- PROCEDURE Tumor Tissue Sample
Study Locations (4)
Alabama
- University of Alabama at Birmingham — Birmingham
California
- University of California, San Francisco — San Francisco
Maryland
- Johns Hopkins University — Baltimore
Missouri
- Washington University in St. Louis — St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-03-06 |
| Est. Completion | 2032-03-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06861244
The ClinicalTrials.gov registry entry for NCT06861244 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francis, which has 1,574 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Embryonal Tumor With Multilayered Rosettes appearing as the primary indexed condition, and to 5 interventions — of which Temozolomide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06861244 reports 4 study locations spanning 4 distinct geographic areas — top geographies include Alabama, California, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06861244 about?
NCT06861244 is a clinical study titled "Embryonal Tumor With Multilayered Rosettes". This is an open-label, comprehensive, iterative investigation of evaluating the use of induction chemotherapy, high-dose chemotherapy, and focal radiation therapy in children with newly diagnosed Embryonal Tumor With Multilayered Rosettes (ETMR).
What is the current status of trial NCT06861244?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2025-03-06. Estimated completion is 2032-03-31.
What conditions does trial NCT06861244 study?
This clinical trial studies the following conditions: Embryonal Tumor With Multilayered Rosettes, Embryonal Tumor With Multilayered Rosettes, Nos. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06861244?
The interventions under investigation include: Temozolomide (DRUG), Radiotherapy (RT) (RADIATION), Chemotherapy Drug, Cancer - Physician's Choice (DRUG), Non-Investigational Surgical Resection (PROCEDURE), Tumor Tissue Sample (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06861244?
This trial is sponsored by University of California, San Francis, which has 1,574 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06861244 being conducted?
This trial has 4 study locations across Alabama, California, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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