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NCT06857448 · ClinicalTrials.gov registry record · NA
Autologous Point-of-Care Adipose Therapy: Recent Injury
A NA study, sponsored by University of Pittsburgh.
- Not yet
- Registry status
- NA
- Development phase
- 68
- Enrollment target
NCT06857448: Clinical Trial NA study, sponsored by University of Pittsburgh.
NCT06857448 is a NA study that has not yet begun recruiting, run by University of Pittsburgh. The registered enrollment target is 68 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06857448, a NA study, has not yet begun recruiting, sponsored by University of Pittsburgh.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
Study Summary
The goal of this study is to explore if an adipose-based therapeutic strategy can treat full-thickness soft-tissue trauma wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can immediate autologous adipose and autologous layered composite grafting be effective for acute functional soft-tissue reconstruction? Researchers will compare the single-stage autologous layered composite grafting method to traditional methods to see if it improves healing outcomes, minimizes scarring, and reduces infection risk. Participants will: * Receive immediate fat grafting into the wound. * Undergo simultaneous split-thickness skin grafting for full soft-tissue reconstruction.
Primary Outcome
POSAS measures subjective assessment on a 1-10 scale from normal skin to worst scar imaginable across 6 metrics (surface area, vascularity, pigmentation, thickness, pliability and relief). The lowest sum score, reflecting normal skin, is 6 and the highest score, reflecting the worst imaginable scar, is 60.
Interventions
- PROCEDURE Split Thickness Skin Graft (STSG)
- PROCEDURE Base of wound fat graft with STSG Reconstruction (Autologous Layered Composite Grafting).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2025-12 |
| Est. Completion | 2028-10-30 |
| Phase | NA |
What is known before NCT06857448 opens enrollment
NCT06857448 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Split Thickness Skin Graft (STSG) is the first listed.
NCT06857448 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06857448 about?
NCT06857448 is a clinical study titled "Autologous Point-of-Care Adipose Therapy: Recent Injury". The goal of this study is to explore if an adipose-based therapeutic strategy can treat full-thickness soft-tissue trauma wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can immediate autologous adipose and autologou...
What is the current status of trial NCT06857448?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 68 participants. The study started on 2025-12. Estimated completion is 2028-10-30.
What interventions are being tested in trial NCT06857448?
The interventions under investigation include: Split Thickness Skin Graft (STSG) (PROCEDURE), Base of wound fat graft with STSG Reconstruction (Autologous Layered Composite Grafting). (PROCEDURE).
Who is sponsoring clinical trial NCT06857448?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06857448's enrollment target sits among peer trials
68 1133rd of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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