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NCT06848309 · ClinicalTrials.gov registry record

Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2

A clinical trial of Influenza and SARS-CoV-2 (COVID-19) Infection, sponsored by Washington University School of Medicine.

Recruiting
Registry status
300
Enrollment target
1
Study location

NCT06848309: Recruiting study of Influenza and SARS-CoV-2 (COVID-19) Infection, sponsored by Washington University School of Medicine.

NCT06848309 is a study of Influenza and SARS-CoV-2 (COVID-19) Infection that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 300 participants, below the 36,802-participant average among 156 other Influenza trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06848309, a study of Influenza and SARS-CoV-2 (COVID-19) Infection, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
300 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the virus-specific immune response in people who are symptomatic with confirmed influenza or COVID-19. We will study the immune response of people who have and who have not been vaccinated with the seasonal influenza and COVID-19 vaccines within the past year. All participants will have data collected and blood, saliva, and nasal swabs performed at five separate visits; 1) at study enrollment, 2) on study day 7, 3) on or between study days 10 to 28, 4) on study day 90, and 5) on study day 180. For participants who agree to the optional sub-study, bronchoscopy with bronchoalveolar lavage (BAL) and endobronchial biopsy (EBBx) will be performed once between study days 10 and 28 and once at study day 180. As part of the bronchoscopy procedure, two chest x-rays will be performed. The bronchoscopy and chest x-ray procedures are not required for participation in the study.

Interventions

  • PROCEDURE Bronchoscopy

Study Locations (1)

Missouri

  • Washington University in Saint Louis Department of Emergency Medicine, Emergency Care Research Core - St Louis

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2025-03-07
Est. Completion 2029-10

What NCT06848309 shows while recruiting

NCT06848309 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 36,802-participant average among 156 other Influenza trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Influenza appearing as the primary indexed condition, and to 1 intervention - of which Bronchoscopy is the first listed.

NCT06848309 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT06848309 about?

NCT06848309 is a clinical study titled "Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2". The purpose of this study is to evaluate the virus-specific immune response in people who are symptomatic with confirmed influenza or COVID-19. We will study the immune response of people who have and who have not been vaccinated with the seasonal influenza and COVID-19 vaccines within the past year...

What is the current status of trial NCT06848309?

This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2025-03-07. Estimated completion is 2029-10.

What conditions does trial NCT06848309 study?

This clinical trial studies the following conditions: Influenza, SARS-CoV-2 (COVID-19) Infection, Immune Response of Host.

What interventions are being tested in trial NCT06848309?

The interventions under investigation include: Bronchoscopy (PROCEDURE).

Who is sponsoring clinical trial NCT06848309?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06848309 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Influenza

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06848309's enrollment target sits among peer trials

300 67th of 156 higher than 85 of 156 other Influenza trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Influenza trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06848309, the US trial registry maintained by the National Library of Medicine. NCT06848309 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.