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A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
NCT06770933 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this clinical trial is to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of VX-01 as stand-alone treatment for Diabetic Retinopathy of Non-Proliferative Type (NPDR). The primary objective of the study is to evaluate the efficacy of daily oral doses of VX-01 versus placebo following 52 weeks of treatment.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG VX-01
Study Locations (20)
New South Wales
- Eye Clinic Albury Wodonga — Albury
- Retina And Eye Consultants Hurstville — Hurstville
- Marsden Eye Specialists — Parramatta
- Sydney Eye Hospital — Sydney
- Sydney Retina Clinic — Sydney
- Sydney West Retina — Westmead
California
- Retina-Vitreous Associates Medical Group — Beverly Hills
- Stanford Byers Eye Institute — Palo Alto
- California Retina Consultants- Santa Barbara — Santa Barbara
Other
- Prince of Wales Hospital The Chinese University of Hong Kong — Shatin
- HKU Eye Centre — Wong Chuk Hang
Florida
- Florida Retina Institute - Jacksonville Southside — Jacksonville
Illinois
- Retina Associates — Elmhurst
Maryland
- Cumberland Valley Retina Consultants — Hagerstown
Pennsylvania
- Erie Retina Research — Erie
Virginia
- Piedmont Eye Center — Lynchburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-02-11 |
| Est. Completion | 2027-03 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06770933
The ClinicalTrials.gov registry entry for NCT06770933 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vantage Biosciences, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Diabetic Retinopathy appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06770933 reports 20 study locations spanning 12 distinct geographic areas — top geographies include New South Wales, California, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06770933 about?
NCT06770933 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01". The goal of this clinical trial is to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of VX-01 as stand-alone treatment for Diabetic Retinopathy of Non-Proliferative Type (NPDR). The primary objective of the study is to evaluate the efficacy of daily oral doses of VX-...
What is the current status of trial NCT06770933?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2025-02-11. Estimated completion is 2027-03.
What conditions does trial NCT06770933 study?
This clinical trial studies the following conditions: Diabetic Retinopathy, NPDR - Non Proliferative Diabetic Retinopathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06770933?
The interventions under investigation include: Placebo (DRUG), VX-01 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06770933?
This trial is sponsored by Vantage Biosciences, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06770933 being conducted?
This trial has 20 study locations across California, Florida, Illinois, Maryland, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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