Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06747715 · ClinicalTrials.gov registry record · NA
Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting
A NA study of Facial Defect, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT06747715 is a NA study of Facial Defect that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 22 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06747715, a NA study of Facial Defect, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruction using autologous fat grafting in wounded service members and veterans. The main questions it aims to answer are: 1. Will treating subjects with post-traumatic craniofacial deformities using fresh fat grafts, followed by a second treatment 3 months later with cryopreserved fat stored at -80°C, improve facial tissue regeneration and appearance? 2. How do volume retention and tissue health change between fresh and cryopreserved grafts in humans? 3. How do factors such as cellular composition of the graft, patient demographics, and medical conditions (including diabetes, tobacco use, medications, age, and BMI) affect fat graft volume retention and overall outcomes? Researchers will compare results from the second-stage cryopreserved fat grafting to fresh fat grafting to assess outcomes like volume retention, patient recovery, and cost reduction. Participants will: Undergo an initial fat grafting procedure. Have additional fat harvested and cryo-stored for use in a second-stage procedure. Receive the cryopreserved fat in a later stage without the need for a second fat harvest. Receive small test injections behind each ear for later analysis. Provide data on demographics and medical conditions for correlation with outcomes.
Conditions Studied
Interventions
- PROCEDURE Serial Fat Grafting Fresh followed by Cryopreserved Fat
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06747715
The ClinicalTrials.gov registry entry for NCT06747715 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Facial Defect appearing as the primary indexed condition, and to 1 intervention - of which Serial Fat Grafting Fresh followed by Cryopreserved Fat is the first listed.
NCT06747715 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06747715 about?
NCT06747715 is a clinical study titled "Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting". The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruction using autologous fat grafting in wounded service members and veterans. The main questions it aims to answer are: 1. Will treating subjec...
What is the current status of trial NCT06747715?
This trial is currently recruiting. It is a NA study. The enrollment target is 22 participants. The study started on 2025-10-01. Estimated completion is 2027-12-31.
What conditions does trial NCT06747715 study?
This clinical trial studies the following conditions: Facial Defect.
What interventions are being tested in trial NCT06747715?
The interventions under investigation include: Serial Fat Grafting Fresh followed by Cryopreserved Fat (PROCEDURE).
Who is sponsoring clinical trial NCT06747715?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06747715 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Facial Defect
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.