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NCT06740266 · ClinicalTrials.gov registry record · NA
The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families
A NA study of Epigenetic Aging and Parent Child Relationship, sponsored by University of Washington.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 1
- Study location
NCT06740266: Recruiting NA study of Epigenetic Aging and Parent Child Relationship, sponsored by University of Washington.
NCT06740266 is a NA study of Epigenetic Aging and Parent Child Relationship that is actively recruiting participants, run by University of Washington. The registered enrollment target is 250 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06740266, a NA study of Epigenetic Aging and Parent Child Relationship, is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health. The investigators will test if the support given to parents of young children reduces childhood stress. The investigators will also test if the effects of mother's stress and Early Life Adversity can be passed down to children. Can it impact the child's long-term health? Researchers will compare the Promoting First Relationships® in Primary Care (PFR in PC) parenting program with Usual Care to see if PFR reduces mothers' stress, improves mother's sensitivity, and reduces accelerated cellular aging. Participants will: * Be randomized to receive PFR in PC or Usual Care. PFR in PC is an evidence-based 10-week home visiting service, with 2 extra sessions at the WakeMed pediatric clinic. Usual Care is the health care and general services offered to families at the WakeMed pediatric clinic. * Have in-home research visits at the start of the study (Time 1, T1), about 6 months later (Time 2, T2), and 12 months later (Time 3, T3). Information collected at these visits includes: * Answering questions about your background, past and current stress, physical and mental health, parenting behaviors, and child behavior problems (T1, T2, T3). * Being videotaped doing a short teaching activity. * Having a small amount of blood collected from the mother by finger prick (T1, T3). * Having a small amount of blood collected from the infant by heel stick (T1, T3).
Primary Outcome
DNA will be extracted from DBS samples using Qiagen's QIAamp DNA Mini Kit. Extracted DNA is quantified using a NanoDrop 2000 spectrophotometer (Thermo Fisher), checked for integrity using TapeStation bioanalyzer and Quant-iT Picogreen (Invitrogen) to specifically determine double-stranded DNA concentration.
Conditions Studied
Interventions
- BEHAVIORAL Promoting First Relationships in Primary Care (PFR-PC)
Study Locations (1)
North Carolina
- WakeMed Health & Hospitals - Raleigh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2024-12-13 |
| Est. Completion | 2029-04 |
| Phase | NA |
What NCT06740266 shows while recruiting
NCT06740266 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 4 conditions, with Epigenetic Aging appearing as the primary indexed condition, and to 1 intervention - of which Promoting First Relationships in Primary Care (PFR-PC) is the first listed.
NCT06740266 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06740266 about?
NCT06740266 is a clinical study titled "The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families". The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health. The investigators will test if the support given to parents of young children reduces childhood stress. The investigators will also test if...
What is the current status of trial NCT06740266?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2024-12-13. Estimated completion is 2029-04.
What conditions does trial NCT06740266 study?
This clinical trial studies the following conditions: Epigenetic Aging, Parent Child Relationship, Child Social-Emotional Development, Telomere Length.
What interventions are being tested in trial NCT06740266?
The interventions under investigation include: Promoting First Relationships in Primary Care (PFR-PC) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06740266?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06740266 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06740266's enrollment target sits among peer trials
250 410th of 2000 higher than 1,567 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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