Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06682767 · ClinicalTrials.gov registry record · NA
A Nutritional Intervention for Body, Brain, and Longevity Effects (NIBBLE)
A NA study, sponsored by Cedars-Sinai Medical Center.
- Not yet
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT06682767: Clinical Trial NA study, sponsored by Cedars-Sinai Medical Center.
NCT06682767 is a NA study that has not yet begun recruiting, run by Cedars-Sinai Medical Center. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06682767, a NA study, has not yet begun recruiting, sponsored by Cedars-Sinai Medical Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
The study aims to evaluate the safety, feasibility, and preliminary efficacy of six-month fasting-mimicking (FMD) relative to Dietary Guidance intervention in middle-aged adults at elevated risk for Alzheimer's disease due to the apolipoprotein (APOE) ε4 allele. Participants randomly assigned to the FMD intervention will consume a FMD for 5-days each month over a period of 6-months.
Primary Outcome
Endpoint: Number of adverse events in the intervention group relative to the Dietary Guidance group
Interventions
- BEHAVIORAL Dietary Guidance
- DIETARY_SUPPLEMENT FMD1 (LNT22-017-1)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-03 |
| Est. Completion | 2027-03 |
| Phase | NA |
What is known before NCT06682767 opens enrollment
NCT06682767 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Dietary Guidance is the first listed.
NCT06682767 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06682767 about?
NCT06682767 is a clinical study titled "A Nutritional Intervention for Body, Brain, and Longevity Effects (NIBBLE)". The study aims to evaluate the safety, feasibility, and preliminary efficacy of six-month fasting-mimicking (FMD) relative to Dietary Guidance intervention in middle-aged adults at elevated risk for Alzheimer's disease due to the apolipoprotein (APOE) ε4 allele. Participants randomly assigned to the...
What is the current status of trial NCT06682767?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-03. Estimated completion is 2027-03.
What interventions are being tested in trial NCT06682767?
The interventions under investigation include: Dietary Guidance (BEHAVIORAL), FMD1 (LNT22-017-1) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06682767?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06682767's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia