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NCT06654466 · ClinicalTrials.gov registry record · NA
Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
A NA study of Hereditary Cancer Syndromes and Clinical Decision Support, sponsored by Nest Genomics.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06654466: Recruiting NA study of Hereditary Cancer Syndromes and Clinical Decision Support, sponsored by Nest Genomics.
NCT06654466 is a NA study of Hereditary Cancer Syndromes and Clinical Decision Support that is actively recruiting participants, run by Nest Genomics. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06654466, a NA study of Hereditary Cancer Syndromes and Clinical Decision Support, is actively recruiting participants, sponsored by Nest Genomics.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to see if a software platform can improve cancer screening in young adults with genetic risk for cancer. The trial will also help improve the software platform (Nest). The main questions it aims to answer are: * Do Nest users know more about their cancer risks and recommended care than non-users? * Do Nest users have less psychological distress than non-users? * Do Nest users share cancer risks with family and other doctors more than non-users? * Are Nest users more likely than non-users to have up-to-date care plans? Researchers will compare Nest users to non-users to see if the Nest users are more likely to do recommended cancer screening. Participants will: * Have a genetic counseling or follow up visit * Take a post-visit survey * Intervention arm only: use the Nest Patient Navigator * Complete screening and follow-up care recommended by doctors
Primary Outcome
A 4-item measure of intervention acceptability on a 5-point Likert response scale designed for a range of stakeholders. Demonstrated to be associated with intervention success.
Conditions Studied
Interventions
- DEVICE Nest, an electronic medical record (EMR)-integrated software platform to deliver longitudinal, genetics-based care at scale.
Study Locations (1)
Massachusetts
- Dana Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-02-10 |
| Est. Completion | 2027-09 |
| Phase | NA |
What NCT06654466 shows while recruiting
NCT06654466 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Hereditary Cancer Syndromes appearing as the primary indexed condition, and to 1 intervention - of which Nest, an electronic medical record (EMR)-integrated software platform to deliver longitudinal, genetics-based care at scale. is the first listed.
NCT06654466 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06654466 about?
NCT06654466 is a clinical study titled "Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer". The goal of this clinical trial is to see if a software platform can improve cancer screening in young adults with genetic risk for cancer. The trial will also help improve the software platform (Nest). The main questions it aims to answer are: * Do Nest users know more about their cancer risks an...
What is the current status of trial NCT06654466?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-02-10. Estimated completion is 2027-09.
What conditions does trial NCT06654466 study?
This clinical trial studies the following conditions: Hereditary Cancer Syndromes, Clinical Decision Support.
What interventions are being tested in trial NCT06654466?
The interventions under investigation include: Nest, an electronic medical record (EMR)-integrated software platform to deliver longitudinal, genetics-based care at scale. (DEVICE).
Who is sponsoring clinical trial NCT06654466?
This trial is sponsored by Nest Genomics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06654466 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hereditary Cancer Syndromes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06654466's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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