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NCT06654219 · ClinicalTrials.gov registry record · NA
Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) Agonist Prior to Anesthesia
A NA study of Pulmonary Aspiration, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 136
- Enrollment target
- 1
- Study location
NCT06654219 is a NA study of Pulmonary Aspiration that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 136 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06654219, a NA study of Pulmonary Aspiration, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 136 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on GLP-1 RAs presenting for upper endoscopy, to determine if prolonged fasting is associated with increased thirst, hunger and anxiety, To determine if signs and symptoms of nausea, vomiting, retching, abdominal bloating, and abdominal pain are present on the day of surgery, to see if there is any variability between preoperative gastric ultrasound assessment and volume of gastric contents visualized on upper endoscopy, to determine time of gastric emptying by serial Gastric ultrasonography (GUS) scans every 2 hours in subjects who presented with an initial at-risk scan, to determine the choice of anesthesia used based on preoperative GUS results, to determine if there were any adverse events recorded in this study group, to determine if duration of GLP-1 RA therapy has an association with residual gastric content (RGC). and to determine if dosing of GLP-1 RA has an association with RGC.
Conditions Studied
Interventions
- OTHER GLP-1 RA users with prolonged fasting instructions
- OTHER GLP-1 RA users with standard NPO instructions
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 136 participants |
| Start Date | 2025-10-30 |
| Est. Completion | 2026-05-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06654219
The ClinicalTrials.gov registry entry for NCT06654219 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas Health Science Center, Houston, which has 732 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pulmonary Aspiration appearing as the primary indexed condition, and to 2 interventions - of which GLP-1 RA users with prolonged fasting instructions is the first listed.
NCT06654219 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06654219 about?
NCT06654219 is a clinical study titled "Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) Agonist Prior to Anesthesia". The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on GLP-1 RAs presenting for upper endoscopy, to determine if prolonged fasting is associated with increased thirst, hunger and anxiety, To dete...
What is the current status of trial NCT06654219?
This trial is currently recruiting. It is a NA study. The enrollment target is 136 participants. The study started on 2025-10-30. Estimated completion is 2026-05-01.
What conditions does trial NCT06654219 study?
This clinical trial studies the following conditions: Pulmonary Aspiration.
What interventions are being tested in trial NCT06654219?
The interventions under investigation include: GLP-1 RA users with prolonged fasting instructions (OTHER), GLP-1 RA users with standard NPO instructions (OTHER).
Who is sponsoring clinical trial NCT06654219?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06654219 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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