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NCT06617494 · ClinicalTrials.gov registry record
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
A clinical trial of Chronic Temporomandibular Disorders (TMD), sponsored by University of Minnesota.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT06617494 is a study of Chronic Temporomandibular Disorders (TMD) that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06617494, a study of Chronic Temporomandibular Disorders (TMD), is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases. Despite advances in understanding TMD pathophysiology, the role of central sensitization, particularly deficient endogenous pain inhibition, remains unclear. The conditioned pain modulation (CPM) test, used to assess pain inhibition in chronic TMD pain, has produced inconsistent results due to varying testing parameters. The proposed cross-sectional study will investigate the efficiency of endogenous pain inhibition in individuals with chronic TMD pain compared to controls by applying noxious and non-noxious stimuli to facial and non-facial sites. The findings aim to clarify the impact of weaker pain inhibition over the face, how the conditioning stimulus' painfulness affects inhibition and the relationship between pain inhibition and fluctuations in TMD pain intensity.
Conditions Studied
Interventions
- OTHER Pain modulation testing
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-09-16 |
| Est. Completion | 2026-12-15 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06617494
The ClinicalTrials.gov registry entry for NCT06617494 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Temporomandibular Disorders (TMD) appearing as the primary indexed condition, and to 1 intervention - of which Pain modulation testing is the first listed.
NCT06617494 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT06617494 about?
NCT06617494 is a clinical study titled "Endogenous Pain Inhibition Deficiency in Chronic TMD Pain". Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases. Despite advances in understanding TMD pathophysiology, the role of central sensitizat...
What is the current status of trial NCT06617494?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2024-09-16. Estimated completion is 2026-12-15.
What conditions does trial NCT06617494 study?
This clinical trial studies the following conditions: Chronic Temporomandibular Disorders (TMD).
What interventions are being tested in trial NCT06617494?
The interventions under investigation include: Pain modulation testing (OTHER).
Who is sponsoring clinical trial NCT06617494?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06617494 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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