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NCT06574048 · ClinicalTrials.gov registry record · Phase 1
Carbon Monoxide Hyperbaric Oxygen With Steroid Therapy
A Phase 1 study, sponsored by University of Nebraska.
- Not yet
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT06574048 is a Phase 1 study that has not yet begun recruiting, run by University of Nebraska. The registered enrollment target is 20 participants.
The verdict
NCT06574048, a Phase 1 study, has not yet begun recruiting, sponsored by University of Nebraska.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
Hyperbaric Oxygen Therapy (HBO) is routine treatment of carbon monoxide (CO) poisoning to prevent delayed neurological sequelae. This study looking to see if neurologic outcomes are improved with the addition of dexamethasone. CO poisoning can initiate a free radical mediated process that can instigate a demyelinating process resulting in long term neurological sequelae in some, but not all patients. In other demyelinating disorders, steroids are a part of first line treatment. HBO is already used for acute CO poisoning, so this pilot study will try to ascertain if the addition of steroids in concert with each hyperbaric oxygen session will yield improved outcomes.
Interventions
- DRUG Dexamethasone
- DRUG saline placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-07 |
| Est. Completion | 2028-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06574048
The ClinicalTrials.gov registry entry for NCT06574048 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Dexamethasone is the first listed.
NCT06574048 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06574048 about?
NCT06574048 is a clinical study titled "Carbon Monoxide Hyperbaric Oxygen With Steroid Therapy". Hyperbaric Oxygen Therapy (HBO) is routine treatment of carbon monoxide (CO) poisoning to prevent delayed neurological sequelae. This study looking to see if neurologic outcomes are improved with the addition of dexamethasone. CO poisoning can initiate a free radical mediated process that can instig...
What is the current status of trial NCT06574048?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2026-07. Estimated completion is 2028-01.
What interventions are being tested in trial NCT06574048?
The interventions under investigation include: Dexamethasone (DRUG), saline placebo (DRUG).
Who is sponsoring clinical trial NCT06574048?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
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