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RECRUITING Phase 1

An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors

NCT06568614 · View on ClinicalTrials.gov ↗

Study Summary

This study is being done to learn more about a new drug called BG-89894 (previously known as SYH2039). Researchers want to see if the drug is safe, how well people can tolerate it, how it moves through the body, and whether it shows any early signs of helping to treat cancer. The information gathered may help guide how future studies are designed. The entire study is expected to last about four years. People who join the study may receive treatment for around six months and will be followed for about 12 months after their treatment ends. The study plans to enroll participants over a three-year period.

Interventions

  • DRUG BG-89894

Study Locations (20)

Beijing Municipality

  • Cancer Hospital Chinese Academy of Medical Sciences — Beijing
  • Beijing Cancer Hospital — Beijing
  • Beijing Tsinghua Changgung Hospital — Beijing

Maryland

  • Sidney Kimmel Comprehensive Cancer At Johns Hopkins — Baltimore

Missouri

  • Washington University School of Medicine — St Louis

New York

  • Columbia University Irving Medical Center — New York

Virginia

  • Next Virginia — Fairfax

New South Wales

  • Blacktown Cancer and Haematology Centre — Blacktown

South Australia

  • Cancer Research South Australia — Adelaide

Victoria

  • St Vincents Hospital — Fitzroy

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2024-10-12
Est. Completion 2028-12-30
Phase Phase 1

Sponsor

BeOne Medicines

138 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06568614

The ClinicalTrials.gov registry entry for NCT06568614 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BeOne Medicines, which has 138 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced or Metastatic MTAP-deleted Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which BG-89894 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06568614 reports 20 study locations spanning 18 distinct geographic areas — top geographies include Beijing Municipality, Maryland, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06568614 about?

NCT06568614 is a clinical study titled "An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors". This study is being done to learn more about a new drug called BG-89894 (previously known as SYH2039). Researchers want to see if the drug is safe, how well people can tolerate it, how it moves through the body, and whether it shows any early signs of helping to treat cancer. The information gathere...

What is the current status of trial NCT06568614?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 140 participants. The study started on 2024-10-12. Estimated completion is 2028-12-30.

What conditions does trial NCT06568614 study?

This clinical trial studies the following conditions: Advanced or Metastatic MTAP-deleted Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06568614?

The interventions under investigation include: BG-89894 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06568614?

This trial is sponsored by BeOne Medicines, which has 138 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06568614 being conducted?

This trial has 20 study locations across Maryland, Missouri, New York, Virginia, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial