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RECRUITING Phase 2

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

NCT06559150 · View on ClinicalTrials.gov ↗

Study Summary

This study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily via standard jet nebulizer over at least 24 weeks, compared to placebo, in subjects with non-cystic fibrosis bronchiectasis (NCFBE).

Interventions

  • DRUG Nebulized Ensifentrine Suspension; 3 mg
  • DRUG Nebulized Placebo Solution

Study Locations (20)

North Carolina

  • University of North Carolina — Chapel Hill
  • Accellacare of Wilmington — Wilmington
  • Southeastern Research Center — Winston-Salem

California

  • So Cal Institute for Respiratory Diseases, Inc. — Los Angeles
  • University of California Davis Medical Center — Sacramento

Georgia

  • Emory University at Saint Joseph Pulmonary Clinic — Atlanta
  • Augusta University — Augusta

Alabama

  • Kirklin Clinic of UAB Hospital — Birmingham

Colorado

  • National Jewish Health Main Campus — Denver

District of Columbia

  • MedStar Georgetown University Hospital — Washington D.C.

Florida

  • University of Miami — Miami

Indiana

  • ASHA Clinical Research — Hammond

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2024-09-11
Est. Completion 2026-09
Phase Phase 2

Sponsor

Verona Pharma

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06559150

The ClinicalTrials.gov registry entry for NCT06559150 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Verona Pharma, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Non-cystic Fibrosis Bronchiectasis appearing as the primary indexed condition, and to 2 interventions — of which Nebulized Ensifentrine Suspension; 3 mg is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06559150 reports 20 study locations spanning 16 distinct geographic areas — top geographies include North Carolina, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06559150 about?

NCT06559150 is a clinical study titled "A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis". This study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily via standard jet nebulizer over at least 24 weeks, compared to placebo, in subjects with non-cystic fibrosis bronchiectasis...

What is the current status of trial NCT06559150?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2024-09-11. Estimated completion is 2026-09.

What conditions does trial NCT06559150 study?

This clinical trial studies the following conditions: Non-cystic Fibrosis Bronchiectasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06559150?

The interventions under investigation include: Nebulized Ensifentrine Suspension; 3 mg (DRUG), Nebulized Placebo Solution (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06559150?

This trial is sponsored by Verona Pharma, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06559150 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial