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NCT06555562 · ClinicalTrials.gov registry record · NA
Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis
A NA study, sponsored by Surf Therapeutics.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT06555562: Completed NA study, sponsored by Surf Therapeutics.
NCT06555562 is a NA study that has completed, run by Surf Therapeutics. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06555562, a NA study, has completed, sponsored by Surf Therapeutics.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
This study is designed to investigate whether non-invasive ultrasound (US) that is optimized for stimulation and can elicit an anti-inflammatory response in people with Inflammatory Arthritis as compared to a sham intervention. The primary endpoint is the change in pro-inflammatory cytokines in blood drawn before and after US. Each participant receives 4 experimental US sessions, one of which is randomly assigned to be placebo.
Primary Outcome
Measure the change before and after ultrasound stimulation by immunoassay of blood plasma after challenge with LPS.
Interventions
- DEVICE Ultrasound Stimulation
- DEVICE Non-active ultrasound stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-01-05 |
| Phase | NA |
What the finished NCT06555562 record still lists
NCT06555562 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Ultrasound Stimulation is the first listed.
NCT06555562 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06555562 about?
NCT06555562 is a clinical study titled "Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis". This study is designed to investigate whether non-invasive ultrasound (US) that is optimized for stimulation and can elicit an anti-inflammatory response in people with Inflammatory Arthritis as compared to a sham intervention. The primary endpoint is the change in pro-inflammatory cytokines in bloo...
What is the current status of trial NCT06555562?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2025-10-01. Estimated completion is 2026-01-05.
What interventions are being tested in trial NCT06555562?
The interventions under investigation include: Ultrasound Stimulation (DEVICE), Non-active ultrasound stimulation (DEVICE).
Who is sponsoring clinical trial NCT06555562?
This trial is sponsored by Surf Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06555562's enrollment target sits among peer trials
16 1871st of 2000 higher than 120 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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