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NCT06538337 · ClinicalTrials.gov registry record · NA
Hypofractionated External Beam Radiotherapy With Adaptive Planning for Endometrial and Cervical Cancers
A NA study of Endometrial Cancer and Cervical Cancer, sponsored by Jonsson Comprehensive Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06538337: Recruiting NA study of Endometrial Cancer and Cervical Cancer, sponsored by Jonsson Comprehensive Cancer Center.
NCT06538337 is a NA study of Endometrial Cancer and Cervical Cancer that is actively recruiting participants, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 60 participants, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06538337, a NA study of Endometrial Cancer and Cervical Cancer, is actively recruiting participants, sponsored by Jonsson Comprehensive Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
After surgery to remove the main endometrial and/or cervical tumor, most women receive radiation therapy. This study uses hypo-fractionated radiation therapy, which is a type of radiation therapy in which the total prescribed dose of radiation is delivered in fewer but larger doses than conventional or standard radiotherapy. This research study aims to determine if hypo-fractionated radiation therapy given after surgery can improve treatment tolerability (i.e., fewer treatments) with comparable side effects. Participants will be in the study for about 5 years: Radiation therapy: * 5 daily treatment sessions of MRI or CT-Guided Stereotactic Body Radiation Therapy (SBRT). * Each treatment session will occur on a weekday (typically consecutive weekdays) and will last approximately an hour. Treatment Follow-Up: * Check-up Appointment and answer questions at 3 months post RT * Check-up Appointments with physical exam every 6 months (+/- 4 weeks) for up to 5 years.
Primary Outcome
Evaluate acute radiation toxicity according to Common Terminology Criteria for Adverse Events, Version 5.0 (CTCAE v5.0). Acute toxicity is defined as treatment-related adverse events occurring within 12 weeks of completion of radiotherapy.
Conditions Studied
Interventions
- RADIATION External beam Radiotherapy
Study Locations (1)
California
- University of California at Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-07-24 |
| Est. Completion | 2032-07-26 |
| Phase | NA |
What NCT06538337 shows while recruiting
NCT06538337 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Endometrial Cancer appearing as the primary indexed condition, and to 1 intervention - of which External beam Radiotherapy is the first listed.
NCT06538337 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06538337 about?
NCT06538337 is a clinical study titled "Hypofractionated External Beam Radiotherapy With Adaptive Planning for Endometrial and Cervical Cancers". After surgery to remove the main endometrial and/or cervical tumor, most women receive radiation therapy. This study uses hypo-fractionated radiation therapy, which is a type of radiation therapy in which the total prescribed dose of radiation is delivered in fewer but larger doses than conventional...
What is the current status of trial NCT06538337?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-07-24. Estimated completion is 2032-07-26.
What conditions does trial NCT06538337 study?
This clinical trial studies the following conditions: Endometrial Cancer, Cervical Cancer.
What interventions are being tested in trial NCT06538337?
The interventions under investigation include: External beam Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT06538337?
This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06538337 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Endometrial Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06538337's enrollment target sits among peer trials
60 117th of 181 higher than 63 of 181 other Endometrial Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Endometrial Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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