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NCT06526260 · ClinicalTrials.gov registry record · NA
Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth
A NA study of Social Anxiety Disorder, sponsored by Children's Hospital Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06526260: Recruiting NA study of Social Anxiety Disorder, sponsored by Children's Hospital Los Angeles.
NCT06526260 is a NA study of Social Anxiety Disorder that is actively recruiting participants, run by Children's Hospital Los Angeles. The registered enrollment target is 80 participants, below the 158-participant average among 32 other Social Anxiety Disorder trials with a reported enrollment target (49% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06526260, a NA study of Social Anxiety Disorder, is actively recruiting participants, sponsored by Children's Hospital Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to identify the circuit activations by very brief exposure (VBE) among youth with social anxiety disorder (SAD) in order to develop a novel intervention for those with SAD. The secondary objectives of this study are to measure the effect of VBE on subjective fear ratings, and participants' awareness and tolerance of the exposure stimuli. * The primary outcome of this study is the mean activation of frontostriatal and prefrontal brain regions to facial stimuli, as measured by Blood Oxygen Level Dependent (BOLD) response, in 4 regions of interest during the magnetic resonance imaging (MRI). * Another primary outcome of the study is to identify networks of regions subserving emotion regulation and attention, as measured by BOLD response of corresponding brain regions. Secondary Outcomes -The secondary outcome of this study is the fear induced by exposure to facial expression stimuli as measured by a 4-point fear scale during the functional magnetic resonance imaging (fMRI) after each block of 10 facial expression stimuli trials. Participants will participate in an interview where they will answer questions both inside and outside of the MRI scan. Participants will be asked to rate on a scale the imagines they see while undergoing MRI scan.
Primary Outcome
A hypothesis-driven, group-level analysis will test brain activity, measured as Blood Oxygen Level Dependent (BOLD) response, in 4 regions of interest while minimizing Type II error.
Conditions Studied
Interventions
- BEHAVIORAL Very Brief Exposure to Facial Expressions
Study Locations (1)
California
- Children's Hospital Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-08-14 |
| Est. Completion | 2026-07 |
| Phase | NA |
What NCT06526260 shows while recruiting
NCT06526260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 158-participant average among 32 other Social Anxiety Disorder trials with a reported enrollment target (49% lower).
The record links to 1 condition, with Social Anxiety Disorder appearing as the primary indexed condition, and to 1 intervention - of which Very Brief Exposure to Facial Expressions is the first listed.
NCT06526260 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06526260 about?
NCT06526260 is a clinical study titled "Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth". The goal of this clinical trial is to identify the circuit activations by very brief exposure (VBE) among youth with social anxiety disorder (SAD) in order to develop a novel intervention for those with SAD. The secondary objectives of this study are to measure the effect of VBE on subjective fear r...
What is the current status of trial NCT06526260?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-08-14. Estimated completion is 2026-07.
What conditions does trial NCT06526260 study?
This clinical trial studies the following conditions: Social Anxiety Disorder.
What interventions are being tested in trial NCT06526260?
The interventions under investigation include: Very Brief Exposure to Facial Expressions (BEHAVIORAL).
Who is sponsoring clinical trial NCT06526260?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06526260 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Social Anxiety Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06526260's enrollment target sits among peer trials
80 18th of 32 higher than 14 of 32 other Social Anxiety Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Social Anxiety Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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