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A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.
NCT06493578 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of VYN201 Gel in subjects with non-segmental vitiligo.
Conditions Studied
Interventions
- DRUG VYN201 Gel
- DRUG Vehicle Gel
Study Locations (20)
California
- California Dermatology & Clinical Research Institute — Encinitas
- First OC Dermatology Research, Inc — Fountain Valley
- Center for Dermatology Clinical Research, Inc — Fremont
- Marvel Clinical Research — Huntington Beach
- Northridge Clinical Trials — Northridge
- Palmtree Clinical Research, Inc. — Palm Springs
- Integrative Skin Science and Research — Sacramento
Florida
- Skin Care Research — Boca Raton
- Driven Research LLC — Coral Gables
- Skin Care Research — Hollywood
- International Clinical Research - FL LLC — Sanford
- Metabolic Research Institute, Inc — West Palm Beach
Arizona
- Saguaro Dermatology — Phoenix
- Center for Dermatology and Plastic Surgery/CCT Research — Scottsdale
- Noble Clinical Research — Tucson
Arkansas
- Clinical Trial Institute of Northwest Arkansas, LLC — Fayetteville
- Burke Pharmaceutical Research — Hot Springs
Colorado
- Clarity Dermatology — Castle Rock
- Colorado Medical Research Center — Denver
Alabama
- Cahaba Dermatology & Skin Health Center — Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-06-04 |
| Est. Completion | 2026-01-30 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06493578
The ClinicalTrials.gov registry entry for NCT06493578 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vyne Therapeutics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Non-segmental Vitiligo appearing as the primary indexed condition, and to 2 interventions — of which VYN201 Gel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06493578 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06493578 about?
NCT06493578 is a clinical study titled "A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.". The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of VYN201 Gel in subjects with non-segmental vitiligo.
What is the current status of trial NCT06493578?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2024-06-04. Estimated completion is 2026-01-30.
What conditions does trial NCT06493578 study?
This clinical trial studies the following conditions: Non-segmental Vitiligo. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06493578?
The interventions under investigation include: VYN201 Gel (DRUG), Vehicle Gel (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06493578?
This trial is sponsored by Vyne Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06493578 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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