Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

NCT06355531 · View on ClinicalTrials.gov ↗

Study Summary

PROSPER trial is a trial to assess the efficacy of FNP-223 in slowing disease progression in participants with PSP as measured by the PSP Rating Scale (PSPRS) over 52 weeks and to assess the safety and tolerability of FNP-223 for 52 weeks in participants with PSP.

Interventions

  • DRUG Placebo
  • DRUG FNP-223

Study Locations (20)

Other

  • Groupe Hospitalier Pellegrin — Bordeaux
  • Hôpital de la Timone — Marseille
  • L'Hôpital Universitaire Carémeau — Nîmes
  • Hôpital Universitaire Pitié Salpêtrière — Paris
  • Hôpital Pierre-Paul Riquet — Toulouse
  • Neurologisches Fachkrankenhaus für Bewegungsstörungen/Parkinson — Beelitz
  • Universitätsklinikum Düsseldorf — Düsseldorf
  • Universitätsklinikum Leipzig — Leipzig

California

  • The Neurology Center of Southern California - Carlsbad — Carlsbad
  • UCSF Weill Institute for Neurosciences — San Francisco

New York

  • Robert & John M. Bendheim Parkinson and Movement Disorders Center at Mount Sinai — New York
  • Columbia University Irving Medical Center — New York

Colorado

  • Rocky Mountain Movement Disorders Center — Denver

Florida

  • University of Miami Miller School of Medicine — Miami

Georgia

  • Augusta University — Augusta

Massachusetts

  • Massachusetts General Hospital — Boston

Michigan

  • Quest Research Institute — Farmington Hills

Trial Details

FieldValue
Enrollment Target 241 participants
Start Date 2024-07-23
Est. Completion 2026-11
Phase Phase 2

Sponsor

Ferrer Internacional S.A.

1 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06355531

The ClinicalTrials.gov registry entry for NCT06355531 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 241 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ferrer Internacional S.A., which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Progressive Supranuclear Palsy appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06355531 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Other, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06355531 about?

NCT06355531 is a clinical study titled "A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)". PROSPER trial is a trial to assess the efficacy of FNP-223 in slowing disease progression in participants with PSP as measured by the PSP Rating Scale (PSPRS) over 52 weeks and to assess the safety and tolerability of FNP-223 for 52 weeks in participants with PSP.

What is the current status of trial NCT06355531?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 241 participants. The study started on 2024-07-23. Estimated completion is 2026-11.

What conditions does trial NCT06355531 study?

This clinical trial studies the following conditions: Progressive Supranuclear Palsy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06355531?

The interventions under investigation include: Placebo (DRUG), FNP-223 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06355531?

This trial is sponsored by Ferrer Internacional S.A., which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06355531 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial