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NCT06349772 · ClinicalTrials.gov registry record · Early Phase 1
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
A Early Phase 1 study of Post Operative Pain, sponsored by Texas Tech University Health Sciences Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06349772 is a Early Phase 1 study of Post Operative Pain that is actively recruiting participants, run by Texas Tech University Health Sciences Center. The registered enrollment target is 130 participants, below the 234-participant average among 56 other Post Operative Pain trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06349772, a Early Phase 1 study of Post Operative Pain, is actively recruiting participants, sponsored by Texas Tech University Health Sciences Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators plan on randomizing study participants to either Exparel or Zynrelef at the closure site of robotic sleeve gastrectomy and assessing their pain control postoperatively both in the hospital and at home. The investigators will measure the outcome of two drugs, Zynrelief, and Exparel on postoperative pain score -using the NRS pin score up to 72 hours after surgery. The total opioid use will be recorded in forms that will be used to measure pain score and total opioid use and will be collected to the Excel sheet. The cost of the drug will be calculated for internal use for Hospital purpose only.
Conditions Studied
Interventions
- DRUG Exparel
- DRUG Zynrelef
Study Locations (1)
Texas
- Texas Tech University Health Sciences Center - Lubbock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2025-12-01 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06349772
The ClinicalTrials.gov registry entry for NCT06349772 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 234-participant average among 56 other Post Operative Pain trials with a reported enrollment target (44% lower). The listed sponsor is Texas Tech University Health Sciences Center, which has 76 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Post Operative Pain appearing as the primary indexed condition, and to 2 interventions - of which Exparel is the first listed.
NCT06349772 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06349772 about?
NCT06349772 is a clinical study titled "Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy". The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators ...
What is the current status of trial NCT06349772?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 130 participants. The study started on 2024-11-01. Estimated completion is 2025-12-01.
What conditions does trial NCT06349772 study?
This clinical trial studies the following conditions: Post Operative Pain.
What interventions are being tested in trial NCT06349772?
The interventions under investigation include: Exparel (DRUG), Zynrelef (DRUG).
Who is sponsoring clinical trial NCT06349772?
This trial is sponsored by Texas Tech University Health Sciences Center, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06349772 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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