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NCT06349772 · ClinicalTrials.gov registry record · Early Phase 1
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
A Early Phase 1 study of Postoperative Pain, sponsored by Texas Tech University Health Sciences Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06349772: Recruiting Early Phase 1 study of Postoperative Pain, sponsored by Texas Tech University Health Sciences Center.
NCT06349772 is a Early Phase 1 study of Postoperative Pain that is actively recruiting participants, run by Texas Tech University Health Sciences Center. The registered enrollment target is 130 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06349772, a Early Phase 1 study of Postoperative Pain, is actively recruiting participants, sponsored by Texas Tech University Health Sciences Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators plan on randomizing study participants to either Exparel or Zynrelef at the closure site of robotic sleeve gastrectomy and assessing their pain control postoperatively both in the hospital and at home. The investigators will measure the outcome of two drugs, Zynrelief, and Exparel on postoperative pain score -using the NRS pin score up to 72 hours after surgery. The total opioid use will be recorded in forms that will be used to measure pain score and total opioid use and will be collected to the Excel sheet. The cost of the drug will be calculated for internal use for Hospital purpose only.
Primary Outcome
this will be measured using a numerical rating scale. The scale is 0-10 with 0 being no pain and 10 being the worst pain of their life
Conditions Studied
Interventions
- DRUG Exparel
- DRUG Zynrelef
Study Locations (1)
Texas
- Texas Tech University Health Sciences Center - Lubbock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2025-12-01 |
| Phase | Early Phase 1 |
What NCT06349772 shows while recruiting
NCT06349772 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (44% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Exparel is the first listed.
NCT06349772 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06349772 about?
NCT06349772 is a clinical study titled "Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy". The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators ...
What is the current status of trial NCT06349772?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 130 participants. The study started on 2024-11-01. Estimated completion is 2025-12-01.
What conditions does trial NCT06349772 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT06349772?
The interventions under investigation include: Exparel (DRUG), Zynrelef (DRUG).
Who is sponsoring clinical trial NCT06349772?
This trial is sponsored by Texas Tech University Health Sciences Center, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06349772 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06349772's enrollment target sits among peer trials
130 38th of 120 higher than 82 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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