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A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
NCT06330064 · View on ClinicalTrials.gov ↗
Study Summary
This study is designed to assess the efficacy and safety of ifinatamab deruxtecan (I-DXD) in the following tumor types: endometrial cancer (EC); head and neck squamous cell carcinoma (HNSCC); pancreatic ductal adenocarcinoma (PDAC); colorectal cancer (CRC); hepatocellular carcinoma (HCC); adenocarcinoma of esophagus, gastroesophageal junction, and stomach (Ad-Eso/GEJ/gastric); urothelial carcinoma (UC); ovarian cancer (OVC); cervical cancer (CC); biliary tract cancer (BTC); human epidermal growth factor 2 (HER2)-low breast cancer (BC); HER2 immunohistochemistry (IHC) 0 BC; and cutaneous melanoma.
Conditions Studied
Interventions
- DRUG Ifinatamab deruxtecan
Study Locations (20)
California
- Los Angeles Cancer Network — Los Angeles
- Valkyrie Clinical Trials — Los Angeles
- Pih Health Hematology Medical Oncology — Whittier
New York
- NYU Langone Health — New York
- Icahn School of Medicine At Mount Sinai Prime — New York
- Clinical Research Alliance — Westbury
Tennessee
- Tn Gynecologic Oncology Group, Llc — Chattanooga
- The West Clinic — Germantown
- SCRI Oncology Partners — Nashville
Texas
- Texas Oncology - West Texas — Amarillo
- Texas Oncology, P.A. — Dallas
- Texas Oncology Gulf Coast — Pearland
Other
- DIABAID — Buenos Aires
- Hospital Aleman — Buenos Aires
- Hospital Sirio Libanes — Caba
Illinois
- Orchard Healthcare Research Inc. — Skokie
Minnesota
- M Health Fairview University of Minnesota Medical Center — Minneapolis
Utah
- University of Utah Hospitals & Clinics — Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 520 participants |
| Start Date | 2024-04-10 |
| Est. Completion | 2028-07-25 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06330064
The ClinicalTrials.gov registry entry for NCT06330064 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 520 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Daiichi Sankyo, which has 157 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Recurrent or Metastatic Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which Ifinatamab deruxtecan is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06330064 reports 20 study locations spanning 10 distinct geographic areas — top geographies include California, New York, Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06330064 about?
NCT06330064 is a clinical study titled "A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)". This study is designed to assess the efficacy and safety of ifinatamab deruxtecan (I-DXD) in the following tumor types: endometrial cancer (EC); head and neck squamous cell carcinoma (HNSCC); pancreatic ductal adenocarcinoma (PDAC); colorectal cancer (CRC); hepatocellular carcinoma (HCC); adenocarci...
What is the current status of trial NCT06330064?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 520 participants. The study started on 2024-04-10. Estimated completion is 2028-07-25.
What conditions does trial NCT06330064 study?
This clinical trial studies the following conditions: Recurrent or Metastatic Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06330064?
The interventions under investigation include: Ifinatamab deruxtecan (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06330064?
This trial is sponsored by Daiichi Sankyo, which has 157 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06330064 being conducted?
This trial has 20 study locations across California, Illinois, Minnesota, New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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