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NCT06300892 · ClinicalTrials.gov registry record
Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections
A clinical trial of Open GI Surgery, sponsored by University of Minnesota.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT06300892: Recruiting study of Open GI Surgery, sponsored by University of Minnesota.
NCT06300892 is a study of Open GI Surgery that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 300 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06300892, a study of Open GI Surgery, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, observational study of patients undergoing open GI surgery. At the time of operation, samples will be collected from the incision site and GI tract. The study will follow patients up to 30 days postoperatively, monitoring for signs of SSI. Samples will be taken from all patients who develop SSI. Sequencing will be performed on a subset of samples based on our specific aims. * Aim 1: conduct a case-control study of patients with SSI and age-, sex-, diagnosis-, and wound class-matched control patients without SSI, comparing microbiome alpha diversity and community composition with 16S RNA sequencing to determine the association with SSI. * Aim 2: identify the strain of bacteria isolated from SSIs using shotgun metagenomic sequencing and determine whether the specific strain was present in the skin and gut at the time of operation.
Primary Outcome
Alpha diversity composition at the surgical incision site at multiple time points
Conditions Studied
Interventions
- OTHER No intervention
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2026-05-01 |
What NCT06300892 shows while recruiting
NCT06300892 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Open GI Surgery appearing as the primary indexed condition, and to 1 intervention - of which No intervention is the first listed.
NCT06300892 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06300892 about?
NCT06300892 is a clinical study titled "Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections". This is a prospective, observational study of patients undergoing open GI surgery. At the time of operation, samples will be collected from the incision site and GI tract. The study will follow patients up to 30 days postoperatively, monitoring for signs of SSI. Samples will be taken from all patien...
What is the current status of trial NCT06300892?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2024-04-01. Estimated completion is 2026-05-01.
What conditions does trial NCT06300892 study?
This clinical trial studies the following conditions: Open GI Surgery.
What interventions are being tested in trial NCT06300892?
The interventions under investigation include: No intervention (OTHER).
Who is sponsoring clinical trial NCT06300892?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06300892 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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