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NCT06285253 · ClinicalTrials.gov registry record · Phase 1
miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
A Phase 1 study, sponsored by Miromatrix Medical.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT06285253: Completed Phase 1 study, sponsored by Miromatrix Medical.
NCT06285253 is a Phase 1 study that has completed, run by Miromatrix Medical. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06285253, a Phase 1 study, has completed, sponsored by Miromatrix Medical.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
The clinical trial will assess the safety of miroliverELAP for the treatment of acute liver failure, severe acute alcohol-associated hepatitis, or acute on chronic liver failure. miroliverELAP is an external liver assist combination product consisting of a single-use MIRO-001 bioengineered liver graft and an extracorporeal blood circuit. miroliverELAP Is intended to support the native (failed) liver for up to 48-hours of continuous treatment to allow time for liver recovery or to identify a transplantable liver.
Primary Outcome
Survival over the duration of miroliverELAP treatment
Interventions
- COMBINATION_PRODUCT miroliverELAP treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2024-10-05 |
| Est. Completion | 2026-01-22 |
| Phase | Phase 1 |
What the finished NCT06285253 record still lists
NCT06285253 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which miroliverELAP treatment is the first listed.
NCT06285253 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06285253 about?
NCT06285253 is a clinical study titled "miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial". The clinical trial will assess the safety of miroliverELAP for the treatment of acute liver failure, severe acute alcohol-associated hepatitis, or acute on chronic liver failure. miroliverELAP is an external liver assist combination product consisting of a single-use MIRO-001 bioengineered liver gra...
What is the current status of trial NCT06285253?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2024-10-05. Estimated completion is 2026-01-22.
What interventions are being tested in trial NCT06285253?
The interventions under investigation include: miroliverELAP treatment (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06285253?
This trial is sponsored by Miromatrix Medical, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06285253's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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