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NCT06284473 · ClinicalTrials.gov registry record · Phase 4
Ketamine as a Supplement to Local Anesthesia for Minor Procedures
A Phase 4 study of Abscess and Pain, Procedural, sponsored by Loyola University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 108
- Enrollment target
- 1
- Study location
NCT06284473 is a Phase 4 study of Abscess and Pain, Procedural that is actively recruiting participants, run by Loyola University. The registered enrollment target is 108 participants, below the 382-participant average among 13 other Abscess trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06284473, a Phase 4 study of Abscess and Pain, Procedural, is actively recruiting participants, sponsored by Loyola University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 108 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial is a double-blind randomized controlled clinical trial of adults and children (ages 7 to less than 70 years). Patients who present to the ED and who undergo minor bedside procedures that require local anesthesia will be divided into two groups: The first group will be treated with 0.7 mg/kg intranasal ketamine as well as standard local anesthesia for the procedure (treatment cohort). The second group will be treated with a volume-based dose of intranasal saline solution as well as standard local anesthesia for the procedure (control cohort). The primary aim is to assess whether patients in the treatment cohort report lower pain scores on the Numerical Rating Scale (NRS-100) when compared to patients in the control cohort. For adult patients, a secondary aim is to compare agitation between the two cohorts using the Richmond Agitation Sedation Scale (RASS) and, for pediatric patients, a secondary aim is to compare alertness between the two cohorts using the University of Michigan Sedation Scale (UMSS). Results obtained from specific procedures will be analyzed on a spectrum of complexity and general length of recovery time. Scientific achievements may include finding a safe and effective way to reduce pain and discomfort during minor procedures in the Emergency Department. Additionally, it would provide opportunities for more research on sub-dissociative doses of ketamine during minor procedures: a topic in which there is still a gap in the published research
Conditions Studied
Interventions
- DRUG Ketamine
- OTHER Saline
Study Locations (1)
Illinois
- Loyola University Medical Center - Maywood
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2022-05-25 |
| Est. Completion | 2028-05-31 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06284473
The ClinicalTrials.gov registry entry for NCT06284473 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 382-participant average among 13 other Abscess trials with a reported enrollment target (72% lower). The listed sponsor is Loyola University, which has 92 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Abscess appearing as the primary indexed condition, and to 2 interventions - of which Ketamine is the first listed.
NCT06284473 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06284473 about?
NCT06284473 is a clinical study titled "Ketamine as a Supplement to Local Anesthesia for Minor Procedures". This trial is a double-blind randomized controlled clinical trial of adults and children (ages 7 to less than 70 years). Patients who present to the ED and who undergo minor bedside procedures that require local anesthesia will be divided into two groups: The first group will be treated with 0.7 mg/...
What is the current status of trial NCT06284473?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 108 participants. The study started on 2022-05-25. Estimated completion is 2028-05-31.
What conditions does trial NCT06284473 study?
This clinical trial studies the following conditions: Abscess, Pain, Procedural, Minor Laceration.
What interventions are being tested in trial NCT06284473?
The interventions under investigation include: Ketamine (DRUG), Saline (OTHER).
Who is sponsoring clinical trial NCT06284473?
This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06284473 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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