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RECRUITING NA

Targeted Plasticity Therapy for PTSD

NCT06266364 · View on ClinicalTrials.gov ↗

Study Summary

Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared to PE with placebo (sham) stimulation in participants with posttraumatic stress disorder (PTSD)

Interventions

  • DEVICE Active VNS stimulation
  • DEVICE Sham VNS stimulation

Study Locations (3)

Texas

  • The University of Texas Health Austin Ambulatory Surgery Center — Austin
  • Baylor University Medical Center — Dallas
  • Texas Biomedical Device Center — Richardson

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-12-30
Est. Completion 2028-06
Phase NA

Sponsor

The University of Texas at Dallas

45 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06266364

The ClinicalTrials.gov registry entry for NCT06266364 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas at Dallas, which has 45 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with PTSD, Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions — of which Active VNS stimulation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06266364 reports 3 study locations spanning 1 distinct geographic area — top geographies include Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06266364 about?

NCT06266364 is a clinical study titled "Targeted Plasticity Therapy for PTSD". Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared to PE with placebo (sham) stimulation in participants with posttraumatic...

What is the current status of trial NCT06266364?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-12-30. Estimated completion is 2028-06.

What conditions does trial NCT06266364 study?

This clinical trial studies the following conditions: PTSD, Post Traumatic Stress Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06266364?

The interventions under investigation include: Active VNS stimulation (DEVICE), Sham VNS stimulation (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06266364?

This trial is sponsored by The University of Texas at Dallas, which has 45 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06266364 being conducted?

This trial has 3 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial