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ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa

NCT06212999 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent Phase 3 studies (INCB 54707-301 \[NCT05620823\] or INCB 54707-302 \[NCT05620836\]).

Interventions

  • DRUG Povorcitinib

Study Locations (20)

Florida

  • Investigative Site US309 — Clearwater
  • Investigative Site US317 — Hialeah
  • Investigative Site US306 — Hollywood
  • Investigative Site US320 — Hollywood
  • Investigative Site US316 — Maitland
  • Investigative Site US227 — Margate
  • Investigative Site US204 — Miami
  • Investigative Site US236 — Miami
  • Investigative Site US321 — North Miami Beach
  • Investigative Site US200 — Ocala
  • Investigative Site US228 — Tampa
  • Investigative Site US201 — Tampa

California

  • Investigative Site US315 — Laguna Niguel
  • Investigative Site US223 — Los Angeles
  • Investigative Site US222 — Oakland
  • Investigative Site US226 — San Diego

Arizona

  • Investigative Site US303 — Phoenix
  • Investigative Site US240 — Scottsdale

Arkansas

  • Investigative Site US307 — Fort Smith
  • Investigative Site US214 — Rogers

Trial Details

FieldValue
Enrollment Target 617 participants
Start Date 2024-01-30
Est. Completion 2026-12-26
Phase Phase 3

Sponsor

Incyte Corporation

163 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06212999

The ClinicalTrials.gov registry entry for NCT06212999 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 617 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 163 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hidradenitis Suppurativa (HS) appearing as the primary indexed condition, and to 1 intervention — of which Povorcitinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06212999 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Florida, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06212999 about?

NCT06212999 is a clinical study titled "A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa". The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent Phase 3 studies (INCB 54707-301 \[NCT05620823\] or INCB 54707-302 \[NCT0...

What is the current status of trial NCT06212999?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 617 participants. The study started on 2024-01-30. Estimated completion is 2026-12-26.

What conditions does trial NCT06212999 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa (HS). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06212999?

The interventions under investigation include: Povorcitinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06212999?

This trial is sponsored by Incyte Corporation, which has 163 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06212999 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial