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NCT06993610 · ClinicalTrials.gov registry record · Phase 2

Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

A Phase 2 study of Hidradenitis Suppurativa (HS), sponsored by Zura Bio.

Recruiting
Registry status
Phase 2
Development phase
225
Enrollment target
20
Study locations

NCT06993610 is a Phase 2 study of Hidradenitis Suppurativa (HS) that is actively recruiting participants, run by Zura Bio. The registered enrollment target is 225 participants, above the 162-participant average among 12 other Hidradenitis Suppurativa (HS) trials with a reported enrollment target (39% higher). The trial reports 20 study locations across 12 states.

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The verdict

NCT06993610, a Phase 2 study of Hidradenitis Suppurativa (HS), is actively recruiting participants, sponsored by Zura Bio.

RECRUITING
Registry status
Phase 2
Development phase
225 participants
Enrollment target
20
Study locations

Study Summary

The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 16 weeks (Period 1) in adults with hidradenitis suppurativa, followed by a 16-week open-label extension period in which all participants will receive tibulizumab (Period 2)

Interventions

  • OTHER Placebo
  • BIOLOGICAL Tibulizumab Dose A
  • BIOLOGICAL Tibulizumab Dose B

Study Locations (20)

California

  • First OC Dermatology Research, Inc. - Irvine
  • Wallace Medical Group, Inc. - Los Angeles
  • Northridge Clinical Trials - Northridge
  • NorCal Clinical Research - Rocklin

Indiana

  • Indiana University School of Medicine - Indianapolis
  • The Indiana Clinical Trials Center - Plainfield

Kentucky

  • Equity Medical LLC (Kentucky) - Bowling Green
  • DS Research of Kentucky, LLC - Louisville

Louisiana

  • DelRicht LLC - Baton Rouge
  • Clinical Trials Management, LLC - Metairie

New York

  • Equity Medical - New York
  • OptiSkin Medical - New York

Ohio

  • Optima Research - Boardman
  • ClinOhio Research Services - Columbus

Arizona

  • Medical Dermatology Specialists (Phoenix) - Phoenix

Florida

  • Florida Academic Dermatology Center - Coral Gables

Trial Details

FieldValue
Enrollment Target 225 participants
Start Date 2025-05-16
Est. Completion 2027-04
Phase Phase 2

Sponsor

Zura Bio

2 total trials

What the Registry Record Tells You About NCT06993610

The ClinicalTrials.gov registry entry for NCT06993610 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 225 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 162-participant average among 12 other Hidradenitis Suppurativa (HS) trials with a reported enrollment target (39% higher). The listed sponsor is Zura Bio, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hidradenitis Suppurativa (HS) appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06993610 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, Indiana, Kentucky.

Frequently Asked Questions

What is clinical trial NCT06993610 about?

NCT06993610 is a clinical study titled "Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense". The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 16 weeks (Period 1) in adults with hidradenitis suppurativa, followed by a 16-week open-label extension period in which all participants will receive tibulizumab (Peri...

What is the current status of trial NCT06993610?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 225 participants. The study started on 2025-05-16. Estimated completion is 2027-04.

What conditions does trial NCT06993610 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa (HS).

What interventions are being tested in trial NCT06993610?

The interventions under investigation include: Placebo (OTHER), Tibulizumab Dose A (BIOLOGICAL), Tibulizumab Dose B (BIOLOGICAL).

Who is sponsoring clinical trial NCT06993610?

This trial is sponsored by Zura Bio, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06993610 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.