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RECRUITING Phase 2

Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

NCT06993610 · View on ClinicalTrials.gov ↗

Study Summary

The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 16 weeks (Period 1) in adults with hidradenitis suppurativa, followed by a 16-week open-label extension period in which all participants will receive tibulizumab (Period 2)

Interventions

  • OTHER Placebo
  • BIOLOGICAL Tibulizumab Dose A
  • BIOLOGICAL Tibulizumab Dose B

Study Locations (20)

California

  • First OC Dermatology Research, Inc. — Irvine
  • Wallace Medical Group, Inc. — Los Angeles
  • Northridge Clinical Trials — Northridge
  • NorCal Clinical Research — Rocklin

Indiana

  • Indiana University School of Medicine — Indianapolis
  • The Indiana Clinical Trials Center — Plainfield

Kentucky

  • Equity Medical LLC (Kentucky) — Bowling Green
  • DS Research of Kentucky, LLC — Louisville

Louisiana

  • DelRicht LLC — Baton Rouge
  • Clinical Trials Management, LLC — Metairie

New York

  • Equity Medical — New York
  • OptiSkin Medical — New York

Ohio

  • Optima Research — Boardman
  • ClinOhio Research Services — Columbus

Arizona

  • Medical Dermatology Specialists (Phoenix) — Phoenix

Florida

  • Florida Academic Dermatology Center — Coral Gables

Trial Details

FieldValue
Enrollment Target 225 participants
Start Date 2025-05-16
Est. Completion 2027-04
Phase Phase 2

Sponsor

Zura Bio

33 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06993610

The ClinicalTrials.gov registry entry for NCT06993610 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 225 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Zura Bio, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hidradenitis Suppurativa (HS) appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06993610 reports 20 study locations spanning 12 distinct geographic areas — top geographies include California, Indiana, Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06993610 about?

NCT06993610 is a clinical study titled "Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense". The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 16 weeks (Period 1) in adults with hidradenitis suppurativa, followed by a 16-week open-label extension period in which all participants will receive tibulizumab (Peri...

What is the current status of trial NCT06993610?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 225 participants. The study started on 2025-05-16. Estimated completion is 2027-04.

What conditions does trial NCT06993610 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa (HS). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06993610?

The interventions under investigation include: Placebo (OTHER), Tibulizumab Dose A (BIOLOGICAL), Tibulizumab Dose B (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06993610?

This trial is sponsored by Zura Bio, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06993610 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial