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NCT06205485 · ClinicalTrials.gov registry record · Phase 3
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
A Phase 3 study of Rectal Cancer, sponsored by Canadian Cancer Trials Group.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 250
- Enrollment target
- 20
- Study locations
NCT06205485 is a Phase 3 study of Rectal Cancer that is actively recruiting participants, run by Canadian Cancer Trials Group. The registered enrollment target is 250 participants, below the 3,163-participant average among 70 other Rectal Cancer trials with a reported enrollment target (92% lower). The trial reports 20 study locations across 5 states.
The verdict
NCT06205485, a Phase 3 study of Rectal Cancer, is actively recruiting participants, sponsored by Canadian Cancer Trials Group.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 250 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study is being done to answer the following questions: Is the chance of rectal cancer responding the same if chemotherapy alone is given before limited surgery compared to chemotherapy and radiation therapy given together before limited surgery? If radiation therapy is not given, is quality of life better?
Conditions Studied
Interventions
- DRUG Capecitabine
- DRUG Leucovorin
- DRUG Oxaliplatin
- RADIATION Radiation
- DRUG Fluoruracil
Study Locations (20)
Illinois
- Rush-Copley Medical Center - Aurora
- Northwestern University - Chicago
- Carle at The Riverfront - Danville
- Northwestern Medicine Cancer Center Kishwaukee - DeKalb
- Carle Physician Group-Effingham - Effingham
- Northwestern Medicine Cancer Center Delnor - Geneva
- Carle Physician Group-Mattoon/Charleston - Mattoon
- Carle Cancer Center - Urbana
California
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care - Irvine
- Los Angeles General Medical Center - Los Angeles
- USC / Norris Comprehensive Cancer Center - Los Angeles
- UC Irvine Health/Chao Family Comprehensive Cancer Center - Orange
Delaware
- Beebe South Coastal Health Campus - Millville
- Helen F Graham Cancer Center - Newark
- Medical Oncology Hematology Consultants PA - Newark
- Beebe Health Campus - Rehoboth Beach
Georgia
- Emory University Hospital Midtown - Atlanta
- Emory University Hospital/Winship Cancer Institute - Atlanta
- Emory Saint Joseph's Hospital - Atlanta
Arizona
- Cancer Center at Saint Joseph's - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2024-06-26 |
| Est. Completion | 2030-06-30 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06205485
The ClinicalTrials.gov registry entry for NCT06205485 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,163-participant average among 70 other Rectal Cancer trials with a reported enrollment target (92% lower). The listed sponsor is Canadian Cancer Trials Group, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Rectal Cancer appearing as the primary indexed condition, and to 5 interventions - of which Capecitabine is the first listed.
NCT06205485 reports 20 study locations spanning 5 distinct geographic areas - top geographies include Illinois, California, Delaware.
Frequently Asked Questions
What is clinical trial NCT06205485 about?
NCT06205485 is a clinical study titled "Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer". This study is being done to answer the following questions: Is the chance of rectal cancer responding the same if chemotherapy alone is given before limited surgery compared to chemotherapy and radiation therapy given together before limited surgery? If radiation therapy is not given, is quality of ...
What is the current status of trial NCT06205485?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 250 participants. The study started on 2024-06-26. Estimated completion is 2030-06-30.
What conditions does trial NCT06205485 study?
This clinical trial studies the following conditions: Rectal Cancer.
What interventions are being tested in trial NCT06205485?
The interventions under investigation include: Capecitabine (DRUG), Leucovorin (DRUG), Oxaliplatin (DRUG), Radiation (RADIATION), Fluoruracil (DRUG).
Who is sponsoring clinical trial NCT06205485?
This trial is sponsored by Canadian Cancer Trials Group, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06205485 being conducted?
This trial has 20 study locations across Arizona, California, Delaware, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.