Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

NCT06118281 · View on ClinicalTrials.gov ↗

Study Summary

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. The participant will need to inject the study medicine into a flat skin surface in there stomach, thigh, or upper arm once every month. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study will last for about 2 years.

Interventions

  • DRUG Placebo
  • DRUG Ziltivekimab

Study Locations (20)

California

  • Valley Clinical Trials — Covina
  • Valley Clinical Trials — Covina
  • UCSD Medical Center — La Jolla
  • Loma Linda University Faculty Medical Clinics — Loma Linda
  • VAGrtrLosAngelesHlthcareSystem — Los Angeles
  • University of Californ LA-UCLA — Los Angeles
  • University Of California Irvine — Orange
  • Kaiser Permanente Viewridge Medical Offices — San Diego
  • San Diego Cardiac Center — San Diego

Alabama

  • Advanced Cardiovascular, LLC — Alexander City
  • Birmingham VA Medical Center — Birmingham
  • Grandview Medical Center — Birmingham
  • Eastern Shore Rsrch Inst, LLC — Fairhope
  • Heart Center Rsrch_Hunstville — Huntsville
  • Mobile Heart USA Health Cardiology Clinic — Mobile

Arizona

  • Mercy Gilbert Medical Center — Gilbert
  • Mayo Clinic Arizona — Phoenix
  • Honor Health — Scottsdale

Arkansas

  • Arkansas Cardiology Clinic — Little Rock
  • Central Arkansas Veteran's Healthcare System — Little Rock

Trial Details

FieldValue
Enrollment Target 10,000 participants
Start Date 2024-06-25
Est. Completion 2026-09-03
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06118281

The ClinicalTrials.gov registry entry for NCT06118281 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 10,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Cardiovascular Risk appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06118281 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06118281 about?

NCT06118281 is a clinical study titled "ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack". The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medi...

What is the current status of trial NCT06118281?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 10,000 participants. The study started on 2024-06-25. Estimated completion is 2026-09-03.

What conditions does trial NCT06118281 study?

This clinical trial studies the following conditions: Cardiovascular Risk, Acute Myocardial Infarction (AMI). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06118281?

The interventions under investigation include: Placebo (DRUG), Ziltivekimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06118281?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06118281 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial