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NCT06094816 · ClinicalTrials.gov registry record · Phase 4
Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study
A Phase 4 study of Salt-Sensitivity of Blood Pressure, sponsored by University of Delaware.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06094816: Recruiting Phase 4 study of Salt-Sensitivity of Blood Pressure, sponsored by University of Delaware.
NCT06094816 is a Phase 4 study of Salt-Sensitivity of Blood Pressure that is actively recruiting participants, run by University of Delaware. The registered enrollment target is 120 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06094816, a Phase 4 study of Salt-Sensitivity of Blood Pressure, is actively recruiting participants, sponsored by University of Delaware.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective of this project is to identify the key salt-sensing regions of the brain and determine the underlying mechanism of sodium sensing. The investigators will assess how the brain responds to an acute increase of salt in the blood using MRI. This will be done during a 30-minute infusion of a saline solution containing 3% salt. One trial will be conducted with a salt sensing channel blocker and one trial without the salt sensing channel blocker. This will help to assess the role of a specific salt sensing channel in the brain. Salt sensitivity of BP will be assessed using 7-day dietary feeding where participants will be given food to consume for 7-days. Comparisons will be made between salt resistant (no change in blood pressure going from low to high salt diets) and salt sensitive adults (a change in blood pressure going from low to high salt diets). The investigators think the changes in MRI will be greater in salt sensitive compared to salt resistant subjects.
Primary Outcome
Intensity of sodium sensing regions of the brain
Conditions Studied
Interventions
- DRUG Furosemide (Diuretic)
- OTHER Hypertonic Saline Infusion
Study Locations (1)
Delaware
- University of Delaware - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2024-03-05 |
| Est. Completion | 2028-07 |
| Phase | Phase 4 |
What NCT06094816 shows while recruiting
NCT06094816 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Salt-Sensitivity of Blood Pressure appearing as the primary indexed condition, and to 2 interventions - of which Furosemide (Diuretic) is the first listed.
NCT06094816 reports a single indexed study location in Delaware.
Frequently Asked Questions
What is clinical trial NCT06094816 about?
NCT06094816 is a clinical study titled "Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study". The overall objective of this project is to identify the key salt-sensing regions of the brain and determine the underlying mechanism of sodium sensing. The investigators will assess how the brain responds to an acute increase of salt in the blood using MRI. This will be done during a 30-minute infu...
What is the current status of trial NCT06094816?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2024-03-05. Estimated completion is 2028-07.
What conditions does trial NCT06094816 study?
This clinical trial studies the following conditions: Salt-Sensitivity of Blood Pressure.
What interventions are being tested in trial NCT06094816?
The interventions under investigation include: Furosemide (Diuretic) (DRUG), Hypertonic Saline Infusion (OTHER).
Who is sponsoring clinical trial NCT06094816?
This trial is sponsored by University of Delaware, which has 106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06094816 being conducted?
This trial has 1 study location across Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Salt-Sensitivity of Blood Pressure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06094816's enrollment target sits among peer trials
120 673rd of 2000 higher than 1,290 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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