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Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
NCT06079671 · View on ClinicalTrials.gov ↗
Study Summary
This is a phase III, randomized, double-blind, placebo-controlled, multi-center, global study to explore the efficacy and safety of volrustomig in women with high-risk LACC (FIGO 2018 stage IIIA to IVA cervical cancer) who have not progressed following platinum-based CCRT.
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL Volrustomig
Study Locations (20)
Georgia
- Research Site — Atlanta
- Research Site — Augusta
- Research Site — Savannah
Louisiana
- Research Site — New Orleans
- Research Site — New Orleans
- Research Site — Shreveport
Arizona
- Research Site — Phoenix
- Research Site — Tucson
California
- Research Site — La Jolla
- Research Site — West Hollywood
New York
- Research Site — New York
- Research Site — Syracuse
Ohio
- Research Site — Cleveland
- Research Site — Columbus
Alabama
- Research Site — Birmingham
Arkansas
- Research Site — Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2023-09-22 |
| Est. Completion | 2030-09-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06079671
The ClinicalTrials.gov registry entry for NCT06079671 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Locally Advanced Cervical Cancer appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06079671 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Georgia, Louisiana, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06079671 about?
NCT06079671 is a clinical study titled "Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)". This is a phase III, randomized, double-blind, placebo-controlled, multi-center, global study to explore the efficacy and safety of volrustomig in women with high-risk LACC (FIGO 2018 stage IIIA to IVA cervical cancer) who have not progressed following platinum-based CCRT.
What is the current status of trial NCT06079671?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 800 participants. The study started on 2023-09-22. Estimated completion is 2030-09-30.
What conditions does trial NCT06079671 study?
This clinical trial studies the following conditions: Locally Advanced Cervical Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06079671?
The interventions under investigation include: Placebo (OTHER), Volrustomig (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06079671?
This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06079671 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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