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Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis
NCT06046222 · View on ClinicalTrials.gov ↗
Study Summary
This study will enroll male and female subjects who are 18 years of age or older with Eosinophilic Granulomatosis With Polyangiitis.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG NS-229
Study Locations (20)
Other
- CHU Nice — Nice
- Hopital Cochin — Paris
- Chu Rangueil — Toulouse
- Istituto Auxologico Italiano IRCCS — Milan
- Fondazione Policlinico Universitario Campus Bio-Medico — Roma
- Azienda Provinciale per i Servizi Sanitari Provincia Autonoma Trento — Trento
- Azienda Ospedaliera Universitaria Integrata Verona — Verona
Ohio
- Cleveland Clinic — Cleveland
- The Ohio State University Wexner Medical Center — Columbus
Ontario
- St Joseph's Healthcare Hamilton — Hamilton
- University of Toronto — Toronto
Colorado
- National Jewish Health — Denver
Minnesota
- Mayo Clinic — Rochester
Pennsylvania
- University of Pennsylvania — Philadelphia
South Carolina
- Medical University of South Carolina — Charleston
Tennessee
- Vanderbilt University Medical Center — Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2023-12-20 |
| Est. Completion | 2026-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06046222
The ClinicalTrials.gov registry entry for NCT06046222 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NS Pharma, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Eosinophilic Granulomatosis With Polyangiitis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06046222 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, Ohio, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06046222 about?
NCT06046222 is a clinical study titled "Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis". This study will enroll male and female subjects who are 18 years of age or older with Eosinophilic Granulomatosis With Polyangiitis.
What is the current status of trial NCT06046222?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2023-12-20. Estimated completion is 2026-07.
What conditions does trial NCT06046222 study?
This clinical trial studies the following conditions: Eosinophilic Granulomatosis With Polyangiitis, Churg-Strauss Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06046222?
The interventions under investigation include: Placebo (DRUG), NS-229 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06046222?
This trial is sponsored by NS Pharma, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06046222 being conducted?
This trial has 20 study locations across Colorado, Minnesota, Ohio, Pennsylvania, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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