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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
NCT05975983 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this revised Phase IIa study is to demonstrate safety of INS018\_055 over 12 weeks in adults with Idiopathic Pulmonary Fibrosis (IPF).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG INS018_055
Study Locations (12)
Texas
- University of Texas Southwestern Medical Center — Dallas
- Metroplex Pulmonary and Sleep Center — McKinney
- Research Centers of America — McKinney
Florida
- Florida Lung Asthma and Sleep Specialist — Celebration
- Central Florida Pulmonary Group, P.A. (CFPG) - Downtown Orlando — Orlando
Alabama
- University of Alabama at Birmingham — Birmingham
Arizona
- HonorHealth Research Institute — Scottsdale
California
- Keck School of Medicine of USC — Los Angeles
North Carolina
- Southeastern Research Center — Winston-Salem
Oklahoma
- University of Oklahoma Health Sciences Center (OUHSC) — Oklahoma City
Pennsylvania
- Temple University Hospital-Temple Lung Center — Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-02-08 |
| Est. Completion | 2026-02-28 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05975983
The ClinicalTrials.gov registry entry for NCT05975983 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is InSilico Medicine Hong Kong Limited, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Idiopathic Pulmonary Fibrosis (IPF) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05975983 reports 12 study locations spanning 9 distinct geographic areas — top geographies include Texas, Florida, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05975983 about?
NCT05975983 is a clinical study titled "Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis". The purpose of this revised Phase IIa study is to demonstrate safety of INS018\_055 over 12 weeks in adults with Idiopathic Pulmonary Fibrosis (IPF).
What is the current status of trial NCT05975983?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2024-02-08. Estimated completion is 2026-02-28.
What conditions does trial NCT05975983 study?
This clinical trial studies the following conditions: Idiopathic Pulmonary Fibrosis (IPF). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05975983?
The interventions under investigation include: Placebo (DRUG), INS018_055 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05975983?
This trial is sponsored by InSilico Medicine Hong Kong Limited, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05975983 being conducted?
This trial has 12 study locations across Alabama, Arizona, California, Florida, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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