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COMPLETED Phase 2

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

NCT05896527 · View on ClinicalTrials.gov ↗

Study Summary

This was a 12-week treatment, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study to evaluate the efficacy and safety of DC-806 in participants with moderate to severe plaque psoriasis. This study evaluated the efficacy, safety, tolerability, and pharmacokinetics (PK) of multiple oral doses of DC-806 in participants with moderate to severe plaque psoriasis.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG DC-806

Study Locations (20)

Florida

  • Driven Research LLC — Coral Gables
  • Kirsch Dermatology - Probity - PPDS — Naples
  • GCP Global Clinical Professionals, LLC — St. Petersburg
  • ForCare Clinical Research - CenExel FCR - PPDS — Tampa

Ontario

  • CCA Medical Research - Probity - PPDS — Ajax
  • SimcoDerm Medical and Surgical Dermatology Centre - Probity - PPDS — Barrie
  • Dermatrials Research — Hamilton
  • Lynderm Research Inc. - Probity - PPDS — Markham

California

  • First OC Dermatology — Fountain Valley
  • Clinical Science Institute — Santa Monica

Indiana

  • The Indiana Clinical Trials Center, PC — Plainfield

Kentucky

  • Dermatology Specialists Research - 501 S 2nd St — Louisville

New York

  • DICE Therapeutics Study Site — New York

Ohio

  • Dermatologists of Southwest Ohio - Probity - PPDS — Mason

Pennsylvania

  • Paddington Testing Company Inc — Philadelphia

Trial Details

FieldValue
Enrollment Target 229 participants
Start Date 2023-05-02
Est. Completion 2024-03-25
Phase Phase 2

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05896527

The ClinicalTrials.gov registry entry for NCT05896527 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 229 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05896527 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Florida, Ontario, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05896527 about?

NCT05896527 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis". This was a 12-week treatment, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study to evaluate the efficacy and safety of DC-806 in participants with moderate to severe plaque psoriasis. This study evaluated the efficacy, safety, tolerability, and pharmacokin...

What is the current status of trial NCT05896527?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 229 participants. The study started on 2023-05-02. Estimated completion is 2024-03-25.

What conditions does trial NCT05896527 study?

This clinical trial studies the following conditions: Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05896527?

The interventions under investigation include: Placebo (OTHER), DC-806 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05896527?

This trial is sponsored by DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05896527 being conducted?

This trial has 20 study locations across California, Florida, Indiana, Kentucky, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial