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NCT05895474 · ClinicalTrials.gov registry record · NA
Safety Assessment of Central Medial Thalamus Stimulation Using Transcranial Focused Ultrasound
A NA study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT05895474: Completed NA study, sponsored by Medical University of South Carolina.
NCT05895474 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05895474, a NA study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purposes of this research study are to investigate closed-loop and personalized focused ultrasound as a technique to study how the brain works and to evaluate the safety and effectiveness of the Attune ATTN201 device. This study will objectively assess brain parenchyma morphology, and neuropsychiatric and neuropsychological function, following Transcranial Focused Ultrasound (tFUS) exposure. Electroencephalographic recordings during parametric sweeps will be obtained for observation of changes in the brain network activity, primarily focused on the Central Medial Thalamus (CMT). The CMT maintains strong network connectivity to the cortex and plays a potent role in sleep induction. tFUS has recently emerged as a powerful tool for targeted deep brain neuromodulation and has, in theory, the ability to modulate the activity of the CMT without affecting overlying tissue.
Primary Outcome
A credibility questionnaire will be used to asses feasibility. The credibility scale maximum is 36 and minimum is 0, a higher ratings means higher credibility score which is a better outcome.
Interventions
- DEVICE Transcranial Focused Ultrasound
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-05-15 |
| Est. Completion | 2025-04-23 |
| Phase | NA |
What the finished NCT05895474 record still lists
NCT05895474 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Transcranial Focused Ultrasound is the first listed.
NCT05895474 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05895474 about?
NCT05895474 is a clinical study titled "Safety Assessment of Central Medial Thalamus Stimulation Using Transcranial Focused Ultrasound". The purposes of this research study are to investigate closed-loop and personalized focused ultrasound as a technique to study how the brain works and to evaluate the safety and effectiveness of the Attune ATTN201 device. This study will objectively assess brain parenchyma morphology, and neuropsych...
What is the current status of trial NCT05895474?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2023-05-15. Estimated completion is 2025-04-23.
What interventions are being tested in trial NCT05895474?
The interventions under investigation include: Transcranial Focused Ultrasound (DEVICE).
Who is sponsoring clinical trial NCT05895474?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05895474's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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