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NCT05869825 · ClinicalTrials.gov registry record · NA
HFNC vs NIPPV Following Extubation
A NA study of Congenital Heart Disease, sponsored by Emory University.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT05869825 is a NA study of Congenital Heart Disease that is actively recruiting participants, run by Emory University. The registered enrollment target is 200 participants, below the 471-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05869825, a NA study of Congenital Heart Disease, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
This study has the goal to determine the best method of respiratory support following extubation after cardiac surgery (CS). After cardiac surgery for Congenital Heart Disease (CHD), patients remain intubated until the cardiac team determines it is safe for the patient to undergo a trial of extubation. Two common methods of respiratory support following extubation are High Flow Nasal Cannula (HFNC) and Non Invasive Positive Pressure Ventilation (NIPPV). There is currently a gap in data comparing High Flow Nasal Cannula and Non-Invasive Positive Pressure Ventilation in infants (age 0-1) in regard to extubation failure and overall outcomes. This study will monitor the health outcomes of 200 infants (0 - 1 year) with CHD following cardiac surgery in the Cardiac Intensive Care Unit (CICU) at Children's Healthcare of Atlanta (CHOA). This will be done by assigning the respiratory support method each child will receive following extubation after cardiac surgery. Health outcomes will be monitored until discharge or until the second instance of extubation failure. Both study arms are standard-of-care respiratory support methods in the CHOA CICU. The investigators aim to determine which of these two methods has fewer risk factors when used with infants.
Conditions Studied
Interventions
- PROCEDURE High Flow Nasal Canula following extubation
- PROCEDURE Non-Invasive Positive Pressure Ventilation following extubation
Study Locations (1)
Georgia
- Arthur M. Blank Hospital | Children's Healthcare of Atlanta - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-02-27 |
| Est. Completion | 2026-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05869825
The ClinicalTrials.gov registry entry for NCT05869825 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 471-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (58% lower). The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Congenital Heart Disease appearing as the primary indexed condition, and to 2 interventions - of which High Flow Nasal Canula following extubation is the first listed.
NCT05869825 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT05869825 about?
NCT05869825 is a clinical study titled "HFNC vs NIPPV Following Extubation". This study has the goal to determine the best method of respiratory support following extubation after cardiac surgery (CS). After cardiac surgery for Congenital Heart Disease (CHD), patients remain intubated until the cardiac team determines it is safe for the patient to undergo a trial of extubati...
What is the current status of trial NCT05869825?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2025-02-27. Estimated completion is 2026-05.
What conditions does trial NCT05869825 study?
This clinical trial studies the following conditions: Congenital Heart Disease.
What interventions are being tested in trial NCT05869825?
The interventions under investigation include: High Flow Nasal Canula following extubation (PROCEDURE), Non-Invasive Positive Pressure Ventilation following extubation (PROCEDURE).
Who is sponsoring clinical trial NCT05869825?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05869825 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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