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NCT05812885 · ClinicalTrials.gov registry record · NA
Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain
A NA study of Chronic Low Back Pain, sponsored by University of Hartford.
- Recruiting
- Registry status
- NA
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT05812885: Recruiting NA study of Chronic Low Back Pain, sponsored by University of Hartford.
NCT05812885 is a NA study of Chronic Low Back Pain that is actively recruiting participants, run by University of Hartford. The registered enrollment target is 34 participants, below the 592-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05812885, a NA study of Chronic Low Back Pain, is actively recruiting participants, sponsored by University of Hartford.
- RECRUITING
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
Low back pain is a significant public health problem, is very prevalent, and is often characterized by the persistence of symptoms. Unfortunately, substantial improvements in people with chronic low back pain are rare, causing most people to live with the pain. People with chronic low back pain may have an exaggerated pain response to nociceptive input into tissues that may also cause symptoms distant from the site of the primary symptoms. Historically, these symptoms were thought to be related to pathoanatomic changes to the muscles, ligaments, or joints. However, the severity of these structural changes weakly correlates with the clinical presentation and, in most cases, is not directly related to diagnostic image findings. Patients with chronic musculoskeletal pain, in general, show signs of local/central sensitization. The central sensitization may appear to be directly correlated with the intensity and duration of pain. Therefore, it is essential to reduce pain intensity and minimize the duration of pain to prevent this from happening. Pain relief for chronic low back pain patients should be aimed at treatments that reduce central excitability and increase central inhibition. Research into chronic low back pain treatment has demonstrated strong evidence that different types of exercise decrease pain and improve quality of life. However, exercise itself may be painful, preventing a person from exercising. Thus, treatments aimed at decreasing pain will improve a person's ability to exercise and participate in activities of daily living. One treatment aimed at reducing central excitability and increasing central inhibition is transcutaneous electrical nerve stimulation (TENS). TENS is a "non-pharmacological" treatment for pain that is inexpensive, safe, and easy to use. Prior studies show that TENS utilizes opioid receptors both spinally and supraspinally to inhibit nociceptive dorsal horn neurons, reduce excitatory neurotransmitter release, and reduce hyperalge
Primary Outcome
Pain at Rest Difference Score Pre-intervention and Post Intervention measured by the Numeric Pain Rating Scale. It starts with the absence of pain (0) and reaches the worst pain imaginable (10).
Conditions Studied
Interventions
- DEVICE TENS
Study Locations (1)
Connecticut
- University of Hartford - West Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2023-11-15 |
| Est. Completion | 2025-07 |
| Phase | NA |
What NCT05812885 shows while recruiting
NCT05812885 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 592-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Chronic Low Back Pain appearing as the primary indexed condition, and to 1 intervention - of which TENS is the first listed.
NCT05812885 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05812885 about?
NCT05812885 is a clinical study titled "Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain". Low back pain is a significant public health problem, is very prevalent, and is often characterized by the persistence of symptoms. Unfortunately, substantial improvements in people with chronic low back pain are rare, causing most people to live with the pain. People with chronic low back pain may ...
What is the current status of trial NCT05812885?
This trial is currently recruiting. It is a NA study. The enrollment target is 34 participants. The study started on 2023-11-15. Estimated completion is 2025-07.
What conditions does trial NCT05812885 study?
This clinical trial studies the following conditions: Chronic Low Back Pain.
What interventions are being tested in trial NCT05812885?
The interventions under investigation include: TENS (DEVICE).
Who is sponsoring clinical trial NCT05812885?
This trial is sponsored by University of Hartford, which has 14 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05812885 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05812885's enrollment target sits among peer trials
34 60th of 71 higher than 11 of 71 other Chronic Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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