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Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
NCT05796375 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this research is to determine whether bladder cancer monitoring can be improved by replacing some cystoscopy procedures with urine testing. Specifically, this study examines whether there are any differences in urinary symptoms, discomfort, number of invasive procedures, anxiety, complications, cancer recurrence or cancer progression when some cystoscopy procedures are replaced with urine testing.
Conditions Studied
Interventions
- PROCEDURE Cystoscopy
- DIAGNOSTIC_TEST Bladder EpiCheck urine test
- DIAGNOSTIC_TEST Xpert Bladder Cancer Monitor urine test
Study Locations (8)
Connecticut
- West Haven VA Medical Center — West Haven
Florida
- Bay Pines VA Healthcare System — Bay Pines
Massachusetts
- VA Boston Jamaica Plains Campus — West Roxbury
Missouri
- VA St.Louis Healthcare System — St Louis
Ohio
- University Hospitals Cleveland Medical Center — Cleveland
South Carolina
- Medical University of South Carolina — Charleston
Texas
- UT Southwestern Medical Center — Dallas
Vermont
- White River Junction Veterans Healthcare System — White River Junction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2023-11-17 |
| Est. Completion | 2028-12-30 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05796375
The ClinicalTrials.gov registry entry for NCT05796375 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is White River Junction Veterans Affairs Medical Center, which has 32 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Non-muscle-invasive Bladder Cancer appearing as the primary indexed condition, and to 3 interventions — of which Cystoscopy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05796375 reports 8 study locations spanning 8 distinct geographic areas — top geographies include Connecticut, Florida, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05796375 about?
NCT05796375 is a clinical study titled "Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance". The purpose of this research is to determine whether bladder cancer monitoring can be improved by replacing some cystoscopy procedures with urine testing. Specifically, this study examines whether there are any differences in urinary symptoms, discomfort, number of invasive procedures, anxiety, comp...
What is the current status of trial NCT05796375?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2023-11-17. Estimated completion is 2028-12-30.
What conditions does trial NCT05796375 study?
This clinical trial studies the following conditions: Non-muscle-invasive Bladder Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05796375?
The interventions under investigation include: Cystoscopy (PROCEDURE), Bladder EpiCheck urine test (DIAGNOSTIC_TEST), Xpert Bladder Cancer Monitor urine test (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05796375?
This trial is sponsored by White River Junction Veterans Affairs Medical Center, which has 32 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05796375 being conducted?
This trial has 8 study locations across Connecticut, Florida, Massachusetts, Missouri, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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