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NCT05762380 · ClinicalTrials.gov registry record · NA
Effect of Iron Supplements on the Growth of Enteric Pathogens
A NA study of Iron Deficiency Anemia and Iron-deficiency, sponsored by Iowa State University.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT05762380: Completed NA study of Iron Deficiency Anemia and Iron-deficiency, sponsored by Iowa State University.
NCT05762380 is a NA study of Iron Deficiency Anemia and Iron-deficiency that has completed, run by Iowa State University. The registered enrollment target is 15 participants, below the 193-participant average among 24 other Iron Deficiency Anemia trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05762380, a NA study of Iron Deficiency Anemia and Iron-deficiency, has completed, sponsored by Iowa State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
Iron supplementation is a common approach to address iron deficiency with recommendations for women of childbearing age, particularly those at risk of iron deficiency. Because of its considerably higher absorption, ferrous sulphate is the common iron compound used in iron supplements. However, concerns about iron supplements arise from the knowledge that a large portion of the supplement consumed is not absorbed. This unabsorbed iron travels to the colon and, in preclinical studies, has been shown to promote the growth of enteric pathogens at the expense of beneficial commensal bacteria and increase infection risk, including the clinical incidence of diarrhea. The objective of this study is to compare the effects of iron as ferrous sulfate (FeSO4) or FeSO4-enriched Aspergillus oryzae (Ao iron) on the growth and virulence of common enteric pathogens using an in vitro fecal fermentation model. Stool samples will be collected from women of reproductive age following ingestion of an iron supplement as either FeSO4 or Ao iron. Stool samples will be spiked with common enteric pathogens, and outcome measures will be determined following in vitro fecal fermentation.
Primary Outcome
Iron uptake of common enteric pathogens will be determined in stool following in vitro fecal fermentation.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Ferrous sulfate
- DIETARY_SUPPLEMENT Ferrous sulfate-enriched Aspergillus oryzae (Ao iron)
Study Locations (1)
Iowa
- Iowa State University - Ames
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2022-06-14 |
| Est. Completion | 2022-08-02 |
| Phase | NA |
What the finished NCT05762380 record still lists
NCT05762380 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 193-participant average among 24 other Iron Deficiency Anemia trials with a reported enrollment target (92% lower).
The record links to 4 conditions, with Iron Deficiency Anemia appearing as the primary indexed condition, and to 2 interventions - of which Ferrous sulfate is the first listed.
NCT05762380 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT05762380 about?
NCT05762380 is a clinical study titled "Effect of Iron Supplements on the Growth of Enteric Pathogens". Iron supplementation is a common approach to address iron deficiency with recommendations for women of childbearing age, particularly those at risk of iron deficiency. Because of its considerably higher absorption, ferrous sulphate is the common iron compound used in iron supplements. However, conce...
What is the current status of trial NCT05762380?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2022-06-14. Estimated completion is 2022-08-02.
What conditions does trial NCT05762380 study?
This clinical trial studies the following conditions: Iron Deficiency Anemia, Iron-deficiency, Iron Deficiency Anaemia Due to Dietary Causes, Iron Deficiency Anemia Treatment.
What interventions are being tested in trial NCT05762380?
The interventions under investigation include: Ferrous sulfate (DIETARY_SUPPLEMENT), Ferrous sulfate-enriched Aspergillus oryzae (Ao iron) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05762380?
This trial is sponsored by Iowa State University, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05762380 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Iron Deficiency Anemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05762380's enrollment target sits among peer trials
15 21st of 24 higher than 4 of 24 other Iron Deficiency Anemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Iron Deficiency Anemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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