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A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control
NCT05705440 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this follow-up study was to describe the safety in subsequent pregnancies in participants who were previously administered the RSVPreF3 maternal vaccine or control during any prior RSV MAT study. The study participants enrolled in this follow-up study received RSVPreF3 maternal vaccination (any dose) or controls during the following prior RSV MAT studies: RSV MAT-001 (NCT03674177), RSV MAT-004 (NCT04126213), RSV MAT-010 (NCT05045144), RSV MAT-011 (NCT04138056), RSV MAT-009 (NCT04605159), RSV MAT-012 (NCT04980391) and RSV MAT-039 (NCT05169905). No intervention was administered in this study. The exposure was the intervention (either RSVPreF3 vaccine or control) received by the study participants in the abovementioned prior RSV MAT studies.
Conditions Studied
Interventions
- OTHER Control
- BIOLOGICAL RSVPreF3 vaccine
Study Locations (20)
Texas
- GSK Investigational Site — Austin
- GSK Investigational Site — Fort Worth
- GSK Investigational Site — Houston
- GSK Investigational Site — Keller
Arizona
- GSK Investigational Site — Phoenix
- GSK Investigational Site — Tucson
California
- GSK Investigational Site — Burbank
- GSK Investigational Site — Los Angeles
Idaho
- GSK Investigational Site — Nampa
- GSK Investigational Site — Nampa
Louisiana
- GSK Investigational Site — Covington
- GSK Investigational Site — Slidell
Michigan
- GSK Investigational Site — Detroit
- GSK Investigational Site — Saginaw
Alabama
- GSK Investigational Site — Mobile
Mississippi
- GSK Investigational Site — Biloxi
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,855 participants |
| Start Date | 2023-02-07 |
| Est. Completion | 2025-01-15 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05705440
The ClinicalTrials.gov registry entry for NCT05705440 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,855 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Respiratory Syncytial Virus Infections appearing as the primary indexed condition, and to 2 interventions — of which Control is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05705440 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Texas, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05705440 about?
NCT05705440 is a clinical study titled "A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control". The purpose of this follow-up study was to describe the safety in subsequent pregnancies in participants who were previously administered the RSVPreF3 maternal vaccine or control during any prior RSV MAT study. The study participants enrolled in this follow-up study received RSVPreF3 maternal vacci...
What is the current status of trial NCT05705440?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,855 participants. The study started on 2023-02-07. Estimated completion is 2025-01-15.
What conditions does trial NCT05705440 study?
This clinical trial studies the following conditions: Respiratory Syncytial Virus Infections. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05705440?
The interventions under investigation include: Control (OTHER), RSVPreF3 vaccine (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05705440?
This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05705440 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Idaho, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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