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NCT05696184 · ClinicalTrials.gov registry record · NA
Mechanisms Preventing Pharyngeal Reflux
A NA study of GERD, sponsored by Medical College of Wisconsin.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT05696184: Recruiting NA study of GERD, sponsored by Medical College of Wisconsin.
NCT05696184 is a NA study of GERD that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 300 participants, above the 148-participant average among 15 other GERD trials with a reported enrollment target (103% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05696184, a NA study of GERD, is actively recruiting participants, sponsored by Medical College of Wisconsin.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
Primary Outcome
All pressure measurements will be recorded at a 35HZ frequency and measured in reference to the atmospheric pressure UES and LES pressures will be measured utilizing the e-sleeve function of the manometric analysis software. All UES, LES and esophageal baseline pressures will be measured as peaks and troughs over 3 tidal volume respiratory cycles at stable resting conditions when no pharyngeal, gastric, esophageal, UES or LES events are present. Type, frequency, amplitude, onset, and duration of
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy
- DIAGNOSTIC_TEST Slow and rapid intra-esophageal infusion
Study Locations (1)
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2013-11-01 |
| Est. Completion | 2026-10-12 |
| Phase | NA |
What NCT05696184 shows while recruiting
NCT05696184 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 148-participant average among 15 other GERD trials with a reported enrollment target (103% higher).
The record links to 1 condition, with GERD appearing as the primary indexed condition, and to 2 interventions - of which Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy is the first listed.
NCT05696184 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05696184 about?
NCT05696184 is a clinical study titled "Mechanisms Preventing Pharyngeal Reflux". The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
What is the current status of trial NCT05696184?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2013-11-01. Estimated completion is 2026-10-12.
What conditions does trial NCT05696184 study?
This clinical trial studies the following conditions: GERD.
What interventions are being tested in trial NCT05696184?
The interventions under investigation include: Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy (DIAGNOSTIC_TEST), Slow and rapid intra-esophageal infusion (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05696184?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05696184 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for GERD
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05696184's enrollment target sits among peer trials
300 2nd of 15 the highest of 15 other GERD trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other GERD trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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