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A Longitudinal, Observational Study of Primary Ciliary Dyskinesia in Adults
NCT05685186 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this observational study is to characterize clinical measures and biomarkers of airway disease in adults with primary ciliary dyskinesia (PCD) and in a group of healthy volunteers (HV) to establish normative values. Lung function, mucociliary clearance, radiological findings, and clinical findings will be assessed. Furthermore, quality of life will be assessed using QOL-PCD, a disease specific questionnaire.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Spirometry
- DIAGNOSTIC_TEST Multiple Breath Washout (MBW)
- DIAGNOSTIC_TEST Mucociliary Clearance (MCC)
- DIAGNOSTIC_TEST CT of the chest
- DIAGNOSTIC_TEST MRI of the chest
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill — Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-03-08 |
| Est. Completion | 2025-06-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05685186
The ClinicalTrials.gov registry entry for NCT05685186 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ReCode Therapeutics, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Primary Ciliary Dyskinesia appearing as the primary indexed condition, and to 5 interventions — of which Spirometry is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05685186 reports 1 study location spanning 1 distinct geographic area — top geographies include North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05685186 about?
NCT05685186 is a clinical study titled "A Longitudinal, Observational Study of Primary Ciliary Dyskinesia in Adults". The goal of this observational study is to characterize clinical measures and biomarkers of airway disease in adults with primary ciliary dyskinesia (PCD) and in a group of healthy volunteers (HV) to establish normative values. Lung function, mucociliary clearance, radiological findings, and clinica...
What is the current status of trial NCT05685186?
This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2023-03-08. Estimated completion is 2025-06-30.
What conditions does trial NCT05685186 study?
This clinical trial studies the following conditions: Primary Ciliary Dyskinesia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05685186?
The interventions under investigation include: Spirometry (DIAGNOSTIC_TEST), Multiple Breath Washout (MBW) (DIAGNOSTIC_TEST), Mucociliary Clearance (MCC) (DIAGNOSTIC_TEST), CT of the chest (DIAGNOSTIC_TEST), MRI of the chest (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05685186?
This trial is sponsored by ReCode Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05685186 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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