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RECRUITING Phase 4

Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease

NCT05671991 · View on ClinicalTrials.gov ↗

Study Summary

The main purpose of the study is to determine if empagliflozin can reduce peritoneal glucose absorption in patients with end stage renal diease (ESRD) on peritoneal dialysis. This is a randomized, placebo controlled, acute crossover study of empagliflozin in an anticipated 30 chronic PD patients, with an 8 week "pre post" open label extension in all 30 patients where they will receive empagliflozin daily.

Interventions

  • DRUG Empagliflozin 10 MG
  • DRUG Empagliflozin 25 mg vs Placebo

Study Locations (1)

Connecticut

  • Yale University — New Haven

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2023-03-01
Est. Completion 2026-06-30
Phase Phase 4

Sponsor

Yale University

1,283 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05671991

The ClinicalTrials.gov registry entry for NCT05671991 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yale University, which has 1,283 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with End Stage Renal Disease on Dialysis appearing as the primary indexed condition, and to 2 interventions — of which Empagliflozin 10 MG is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05671991 reports 1 study location spanning 1 distinct geographic area — top geographies include Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05671991 about?

NCT05671991 is a clinical study titled "Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease". The main purpose of the study is to determine if empagliflozin can reduce peritoneal glucose absorption in patients with end stage renal diease (ESRD) on peritoneal dialysis. This is a randomized, placebo controlled, acute crossover study of empagliflozin in an anticipated 30 chronic PD patients, w...

What is the current status of trial NCT05671991?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2023-03-01. Estimated completion is 2026-06-30.

What conditions does trial NCT05671991 study?

This clinical trial studies the following conditions: End Stage Renal Disease on Dialysis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05671991?

The interventions under investigation include: Empagliflozin 10 MG (DRUG), Empagliflozin 25 mg vs Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05671991?

This trial is sponsored by Yale University, which has 1,283 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05671991 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial