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NCT05652218 · ClinicalTrials.gov registry record · NA
REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)
A NA study of Heart Failure (HF) and Left Bundle-Branch Block, sponsored by Inova Health Care Services.
- Active
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 2
- Study locations
NCT05652218: Active NA study of Heart Failure (HF) and Left Bundle-Branch Block, sponsored by Inova Health Care Services.
NCT05652218 is a NA study of Heart Failure (HF) and Left Bundle-Branch Block that is active but no longer recruiting, run by Inova Health Care Services. The registered enrollment target is 21 participants, below the 171-participant average among 3 other Heart Failure (HF) trials with a reported enrollment target (88% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05652218, a NA study of Heart Failure (HF) and Left Bundle-Branch Block, is active but no longer recruiting, sponsored by Inova Health Care Services.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 2
- Study locations
Study Summary
Primary Objective - To determine if implantation of a permanent CRT pacing device (with LB-CRT, or conventional BiV-CRT with a coronary sinus LV lead) can improve electromechanical function, HF symptoms, and natriuretic peptide levels among patients with symptomatic HF, LVEF \> 35%, and LBBB.
Primary Outcome
Myocardial performance index (MPI), a global measure of cardiac performance is defined using tissue Doppler imaging.
Conditions Studied
Interventions
- DEVICE LB-CRT
- DEVICE BIV-CRT
Study Locations (2)
North Carolina
- Duke University Medical Center - Durham
Virginia
- Inova Health System - Falls Church
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2023-02-26 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What the registry record for NCT05652218 still lists
NCT05652218 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 171-participant average among 3 other Heart Failure (HF) trials with a reported enrollment target (88% lower).
The record links to 3 conditions, with Heart Failure (HF) appearing as the primary indexed condition, and to 2 interventions - of which LB-CRT is the first listed.
NCT05652218 reports a single indexed study location in North Carolina, Virginia.
Frequently Asked Questions
What is clinical trial NCT05652218 about?
NCT05652218 is a clinical study titled "REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)". Primary Objective - To determine if implantation of a permanent CRT pacing device (with LB-CRT, or conventional BiV-CRT with a coronary sinus LV lead) can improve electromechanical function, HF symptoms, and natriuretic peptide levels among patients with symptomatic HF, LVEF \> 35%, and LBBB.
What is the current status of trial NCT05652218?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 21 participants. The study started on 2023-02-26. Estimated completion is 2026-03-31.
What conditions does trial NCT05652218 study?
This clinical trial studies the following conditions: Heart Failure (HF), Left Bundle-Branch Block, Left Ventricular Ejection Fraction.
What interventions are being tested in trial NCT05652218?
The interventions under investigation include: LB-CRT (DEVICE), BIV-CRT (DEVICE).
Who is sponsoring clinical trial NCT05652218?
This trial is sponsored by Inova Health Care Services, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05652218 being conducted?
This trial has 2 study locations across North Carolina, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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